Results 1 to 10 of about 6,537 (217)
Antioxidants, 2023 (1) Background: cystamine and its reduced form cysteamine have radioprotective/antioxidant effects in vivo. In this study, we use an in vitro model system to examine the behavior of cystamine towards the reactive primary species produced during the ...
Jintana Meesungnoen +2 more
exaly +4 more sources
Frontiers in Neurology, 2019 Current medications for neurodegenerative and neuropsychiatric diseases such as Alzheimer's disease (AD), Huntington's disease (HD), Parkinson's disease (PD), and Schizophrenia mainly target disease symptoms.
Bindu Paul +2 more
exaly +4 more sources
Synthesis and Characterization of Healable Waterborne Polyurethanes with Cystamine Chain Extenders
Molecules, 2019 In this study, environmentally friendly, self-healing waterborne polyurethanes (WPUs) were prepared based on the disulfide metathesis reaction in cystamine.
Dai Soo Lee
exaly +4 more sources
Molecules, 2023 (1) Background: Radioprotective agents have garnered considerable interest due to their prospective applications in radiotherapy, public health medicine, and situations of large-scale accidental radiation exposure or impending radiological emergencies ...
Samafou Penabeï +4 more
doaj +2 more sources
Effect of Cystamine on Sperm and Antioxidant Parameters of Ram Semen Stored at 4 °C for 50 Hours [PDF]
Archives of Razi Institute, 2021 Physical and chemical changes caused by oxidative stress in the spermatozoa membrane can reduce spermatozoa function and even lead to death. Cystamine (NH2-CH2-CH2-SH, β-mercaptoethylamine) is a natural substance that modulates the endocrine and ...
J Jumintono +9 more
doaj +2 more sources
Pharmaceutics, 2020 Cystamine-based polymers may help to achieve controlled and targeted drug delivery to the colon due to their susceptibility to breakage of the disulfide linkage in the low redox potential environment of the colon.
Yoke Mooi Ng +3 more
doaj +2 more sources
Comparative Analysis of Cystamine and Cysteamine as Radioprotectors and Antioxidants: Insights from Monte Carlo Chemical Modeling under High Linear Energy Transfer Radiation and High Dose Rates. [PDF]
Int J Mol SciThis study conducts a comparative analysis of cystamine (RSSR), a disulfide, and cysteamine (RSH), its thiol monomer, to evaluate their efficacy as radioprotectors and antioxidants under high linear energy transfer (LET) and high-dose-rate irradiation ...
Penabeï S, Meesungnoen J, Jay-Gerin JP.
europepmc +2 more sources
Cystamine preparations exhibit anticoagulant activity.
PLoS ONE, 2015 Transglutaminases are a superfamily of isoenzymes found in cells and plasma. These enzymes catalyze the formation of ε-N-(γ-glutamyl)-lysyl crosslinks between proteins.
Maria M Aleman +5 more
doaj +4 more sources
Cystamine reduces neurodegeneration and epileptogenesis following soman-induced status epilepticus in rats [PDF]
Experimental Biology and MedicineAcute exposure to a seizure-inducing dose of an organophosphorus nerve agent inhibits acetylcholinesterase, leading to pharmacoresistance if benzodiazepine treatment is delayed.
Abiel K. Biney +6 more
doaj +2 more sources
Inhibition of Low-Density Lipoprotein Oxidation by Cysteamine, Cystamine, Cysteine and Cystine at Lysosomal pH and pH 7.4 [PDF]
AntioxidantsLDL can be oxidised in the lysosomes of macrophages. Cysteamine, a thiol antioxidant that accumulates in lysosomes, inhibits the oxidation of LDL by iron at lysosomal pH (pH 4.5) and protects against atherosclerosis in mice.
Emily J. Parkes +8 more
doaj +2 more sources