Results 41 to 50 of about 3,558 (177)

Serotonylation of vascular proteins important to contraction. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Serotonin (5-hydroxytryptamine, 5-HT) was named for its source (sero-) and ability to modify smooth muscle tone (tonin). The biological effects of 5-HT are believed to be carried out by stimulation of serotonin receptors at the plasma membrane.
Stephanie W Watts   +2 more
doaj   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

open access: yesSmart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song   +6 more
wiley   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao   +5 more
wiley   +1 more source

The effect of transglutaminase-2 inhibitor on pulmonary vascular remodeling in rats with pulmonary arterial hypertension

open access: yesClinical and Experimental Hypertension, 2022
To investigate the relationship between transglutaminase type 2 (TG2) and pulmonary vascular remodeling in the formation of pulmonary arterial hypertension (PAH), and to investigate the effect of the inhibitor cystamine dihydrochloride on pulmonary ...
Ting Wang   +4 more
doaj   +1 more source

Sulfur Amino Acids in Diet-induced Fatty Liver: A New Perspective Based on Recent Findings

open access: yesMolecules, 2014
The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it.
John I. Toohey
doaj   +1 more source

Preparation and Properties of Redox-Responsive Micelles Based on Carboxylmethyl Hydroxypropyl Chitosan [PDF]

open access: yesBIO Web of Conferences
By employing carboxymethyl hydroxypropyl chitosan (HPCMS) as the hydrophilic unit, deoxycholic acid (DOCA) as the hydrophobic unit, and cystamine (CYS) as the linker, the synthesis involved a two-step amidation process.
Liu Jianrui, Zhang Yongqin
doaj   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

open access: yesExploration, Volume 6, Issue 3, June 2026.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang   +7 more
wiley   +1 more source

Sulfur‐Rich Sustainable Copolymers for Enhancing Redox Kinetics and Alleviating Cathode Passivation in Lithium‐Sulfur Batteries

open access: yesExploration, Volume 6, Issue 3, June 2026.
A molecularly engineered, sustainable sulfur‐rich redox copolymer cathode delivers accelerated sulfur conversion and suppressed passivation, enabling high sulfur utilization and durable, high‐performance LiS batteries. ABSTRACT Lithium‐sulfur (Li‐S) batteries are promising candidates for advanced energy storage systems.
Sangeeta Sahu   +8 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase and glutathione reductase activity in methemoglobin reduction by methylene blue and cyst amine: study on glucose-6-phosphate dehydrogenase-deficient individuals, on normal subjects and on riboflavin-treated subjects

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1988
The authors have standardized methods for evaluation of the activity of the glucose-6-phosphate dehydrogenase and of glutathione reductase. The general principle of the first method was based on methemoglobin formation by sodium nitrite followed by ...
Benedito Barraviera   +5 more
doaj   +1 more source

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He   +7 more
wiley   +1 more source

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