Results 51 to 60 of about 3,558 (177)
Advanced Functional Materials, Volume 36, Issue 40, 18 May 2026.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma. [PDF]
PLoS ONE, 2014 Most meningiomas are benign, but some clinical-aggressive tumors exhibit brain invasion and cannot be resected without significant complications. To identify molecular markers for these clinically-aggressive meningiomas, we performed microarray analyses ...
Yin-Cheng Huang +9 more
doaj +1 more source
Advanced Science, Volume 13, Issue 30, 28 May 2026.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
The Enzymatic Breakdown of Pantethine to Pantothenic Acid and Cystamine [PDF]
European Journal of Biochemistry, 1970 The enzyme splitting pantethine into pantothenic acid and cystamine has been purified about 3000 times starting from horse kidney. The purification procedure is reported. The enzyme, whose optimal activity lies in the pH range 4.0–5.5, requires the presence of a reduced thiol for the full activity: mercaptoethanol and dithiothreitol give the higher ...
S, Duprè +4 more
openaire +2 more sources
Millimeter‐Scale Dual‐Opposing RNA‐Gradient Hydrogel for Interfacial Gene Silencing
Advanced Science, Volume 13, Issue 29, 22 May 2026.A branched microfluidic platform enables the fabrication of millimeter‐scale hydrogels with dual‐opposing RNA‐gradients for precise spatial control of cell gene expression. This device allows for the generation of multiple constructs at once, offering potential for future engineering of complex tissue interfaces with improved physiological relevance ...
Tyler Hoffman +11 more
wiley +1 more source
Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo [PDF]
Bioscience Reports, 2018 Cystamine is commonly used as a transglutaminase inhibitor. This disulphide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either cystamine or cysteamine, which depends on the local redox environment.
Jeitner, Thomas M. +2 more
openaire +2 more sources
Analysis &Sensing, Volume 6, Issue 3, May 2026.Electrostatic interactions between anionic arsenite and cationic cysteamine‐functionalized gold nanoparticles induce aggregation, producing distinct colorimetric and spectroscopic responses. This simple sensing strategy enables sensitive and selective arsenic(III) detection in aqueous and solid‐supported formats.
Jenisha John Peter, Mindy Levine
wiley +1 more source
SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
Small, Volume 22, Issue 28, 18 May 2026.This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
Engineered Biopolymer Architectures for Selective Metal Ions Extraction
Advanced Sustainable Systems, Volume 10, Issue 4, April 2026.This review establishes a mechanism‐oriented framework that connects biopolymer chemistry, structural engineering, ligand design, and hydrometallurgical process variables for selective metal‐ion extraction. It analyzes how functional groups, hierarchical architectures, and solution speciation govern adsorption capacity and selectivity in acidic ...
Amir Nobahar +4 more
wiley +1 more source
MoleculesAlzheimer’s disease (AD) is a complex neurodegenerative disease that can lead to the loss of cognitive function. The progression of AD is regulated by multiple signaling pathways and their associated targets.
Xiuyuan Wu +8 more
doaj +1 more source