Results 61 to 70 of about 7,096 (220)

Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells [PDF]

open access: yes, 2016
A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide Dendrimers, or BAPAD).[1] The ...
Collado, Daniel   +6 more
core  

Synthesis of oligonucleotides carrying anchoring groups and their use in the preparation of oligonucleotide-gold conjugates [PDF]

open access: yes, 2002
Oligodeoxynucleotide conjugates 1-15 carrying anchoring groups such as amino, thiol, pyrrole, and carboxy groups were prepared. A post-synthetic modification protocol was developed.
Aviñó, Anna   +3 more
core   +1 more source

The effect of transglutaminase-2 inhibitor on pulmonary vascular remodeling in rats with pulmonary arterial hypertension

open access: yesClinical and Experimental Hypertension, 2022
To investigate the relationship between transglutaminase type 2 (TG2) and pulmonary vascular remodeling in the formation of pulmonary arterial hypertension (PAH), and to investigate the effect of the inhibitor cystamine dihydrochloride on pulmonary ...
Ting Wang   +4 more
doaj   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

open access: yesSmall, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi   +14 more
wiley   +1 more source

Sulfur Amino Acids in Diet-induced Fatty Liver: A New Perspective Based on Recent Findings

open access: yesMolecules, 2014
The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it.
John I. Toohey
doaj   +1 more source

Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d) [PDF]

open access: yes, 2006
Calpains are a large family of Ca2+-dependent cysteine proteases that are ubiquitously distributed across most cell types and vertebrate species. Calpains play a role in cell differentiation, apoptosis, cytoskeletal remodeling, signal transduction and ...
Croall   +13 more
core   +2 more sources

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He   +7 more
wiley   +1 more source

Preparation and Properties of Redox-Responsive Micelles Based on Carboxylmethyl Hydroxypropyl Chitosan [PDF]

open access: yesBIO Web of Conferences
By employing carboxymethyl hydroxypropyl chitosan (HPCMS) as the hydrophilic unit, deoxycholic acid (DOCA) as the hydrophobic unit, and cystamine (CYS) as the linker, the synthesis involved a two-step amidation process.
Liu Jianrui, Zhang Yongqin
doaj   +1 more source

Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]

open access: yes, 2016
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
core   +2 more sources

Osteolathyrogenic Action of Mercaptoethylamine and of Cystamine.

open access: yesExperimental Biology and Medicine, 1958
SummaryThe osteolathyrogenic action of β-mercaptoethylamine (cysteamine), when fed to rats as the hydrochloride, was confirmed. Cystamine was found to have similar properties. Gross and microscopic skeletal changes were similar to those produced by osteolathyrogenic nitriles.
W, DASLER, R V, MILLISER
openaire   +2 more sources

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