Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells [PDF]
A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide Dendrimers, or BAPAD).[1] The ...
Collado, Daniel +6 more
core
Synthesis of oligonucleotides carrying anchoring groups and their use in the preparation of oligonucleotide-gold conjugates [PDF]
Oligodeoxynucleotide conjugates 1-15 carrying anchoring groups such as amino, thiol, pyrrole, and carboxy groups were prepared. A post-synthetic modification protocol was developed.
Aviñó, Anna +3 more
core +1 more source
To investigate the relationship between transglutaminase type 2 (TG2) and pulmonary vascular remodeling in the formation of pulmonary arterial hypertension (PAH), and to investigate the effect of the inhibitor cystamine dihydrochloride on pulmonary ...
Ting Wang +4 more
doaj +1 more source
SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
Sulfur Amino Acids in Diet-induced Fatty Liver: A New Perspective Based on Recent Findings
The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it.
John I. Toohey
doaj +1 more source
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d) [PDF]
Calpains are a large family of Ca2+-dependent cysteine proteases that are ubiquitously distributed across most cell types and vertebrate species. Calpains play a role in cell differentiation, apoptosis, cytoskeletal remodeling, signal transduction and ...
Croall +13 more
core +2 more sources
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
Preparation and Properties of Redox-Responsive Micelles Based on Carboxylmethyl Hydroxypropyl Chitosan [PDF]
By employing carboxymethyl hydroxypropyl chitosan (HPCMS) as the hydrophilic unit, deoxycholic acid (DOCA) as the hydrophobic unit, and cystamine (CYS) as the linker, the synthesis involved a two-step amidation process.
Liu Jianrui, Zhang Yongqin
doaj +1 more source
Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]
The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
core +2 more sources
Osteolathyrogenic Action of Mercaptoethylamine and of Cystamine.
SummaryThe osteolathyrogenic action of β-mercaptoethylamine (cysteamine), when fed to rats as the hydrochloride, was confirmed. Cystamine was found to have similar properties. Gross and microscopic skeletal changes were similar to those produced by osteolathyrogenic nitriles.
W, DASLER, R V, MILLISER
openaire +2 more sources

