Functional poly(2-oxazoline)s by direct amidation of methyl ester side chains [PDF]
Poly(2-alkyl/aryl-2-oxazoline)s (PAOx) are biocompatible pseudopolypeptides that have received significant interest for biomedical applications in recent years.
Hoogenboom, Richard, Mees, Maarten
core +2 more sources
Example of Disulfide Conformational Change in the Solid State: Preparation, Optical Properties, and X-ray Studies of a Cystamine-Based Iodoplombate Hybrid [PDF]
A novel cystamine-based hybrid, namely, α-[NH3(CH2)2SS(CH2)2NH3PbI6]·2H3O (1a), was prepared under solvothermal conditions. Interestingly, 1a, which is built up from isolated PbI6 octahedra, can be easily changed into its polymorph, namely, β-[NH3(CH2)2S–
Aragoni +25 more
core +4 more sources
Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin +10 more
wiley +1 more source
Dynamic Covalent Polymeric Foams: En Route to a Sustainable Lightness
Dynamic covalent polymer foams (DCPFs) combine lightweight cellular structures with adaptive polymer networks, enabling self‐healing, reprocessability, and recyclability. By integrating reversible covalent bonds into foam architectures, these materials open new pathways toward sustainable porous polymers within a circular materials economy.
Antoine Adjaoud +3 more
wiley +1 more source
PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Alzheimer’s disease (AD) is a complex neurodegenerative disease that can lead to the loss of cognitive function. The progression of AD is regulated by multiple signaling pathways and their associated targets.
Xiuyuan Wu +8 more
doaj +1 more source
Gut microbiome‐derived metabolites show promise in cancer research and therapy
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang +4 more
wiley +1 more source
Cutting fluid wastewater contains a large amount of emulsified oil. If it is discharged directly without treatment, it will cause environmental pollution and water ecosystem destruction.
LIU Yaowei +5 more
doaj +1 more source
Analysis of tissue transglutaminase function in the migration of swiss 3T3 fibroblasts - the active-state conformation of the enzyme does not affect cell motility but is important for its secretion [PDF]
Increasing evidence suggests that tissue transglutaminase (tTGase; type II) is externalized from cells, where it may play a key role in cell attachment and spreading and in the stabilization of the extracellular matrix (ECM) through protein cross-linking.
Achyuthan +44 more
core +2 more sources

