Results 91 to 100 of about 4,936 (212)

Cystamine-crosslinked and nanozyme decorated polyacrylic acid-based composite microgel of dual functionality: delivery and controlled doxorubicin release

Applied Surface Science Advances
Developing new and improving existing systems for controlled drug release is one of the top tasks of biomaterials science nowadays. The current work aims to develop an efficiently controlled doxorubicin release system based on composite hydrogel formed ...
Patrycja Koscielniak, Maria Sawicka, Ilya Sterin, Kamil Marcisz, Klaudia Kaniewska, Marcin Karbarz, Evgeny Katz, Oleh Smutok   +7 more
doaj   +1 more source

Biocleavable Polycationic Micelles as Highly Efficient Gene Delivery Vectors

Nanoscale Research Letters, 2010
An amphiphilic disulfide-containing polyamidoamine was synthesized by Michael-type polyaddition reaction of piperazine to equimolar N, N′-bis(acryloyl)cystamine with 90% yield.
Zhang Min, Xue Ya-Nan, Liu Min, Zhuo Ren-Xi, Huang Shi-Wen   +4 more
doaj   +1 more source

Cystamine suppresses polyalanine toxicity in a mouse model of oculopharyngeal muscular dystrophy

, 2010
Oculopharyngeal muscular dystrophy (OPMD) is caused by a trinucleotide repeat expansion mutation in the coding region of the gene encoding PABPN1 (polyadenylate-binding protein nuclear 1). Mutant PABPN1 with a polyalanine tract expansion forms aggregates
Sarkar, Sovan, Rubinsztein, David C, Rose, Claudia, Davies, Janet E   +3 more
core   +1 more source

Analysis of covalent adaptable networks Based on disulfide exchange through broadband dielectric spectroscopy

Polymer Testing
To study the nature and the cooperativity of the disulfide exchange mechanism in covalent adaptable networks, the dielectric and conductive properties of three membranes obtained by curing diglycidyl ether of bisphenol A (DGEBA) with hexamethylenediamine
B. Pascual-Jose, R. Teruel-Juanes, S. de la Flor, A. Serra, A. Ribes-Greus   +4 more
doaj   +1 more source

The Effect of Cystamine on Acute Radiotoxicity of P32 in Mice

, 1961
SummaryA total of 240 DBA I mice were given one intraperitoneal injection of P32. The experimental group was given a 0.2 percent aqueous solution of cystamine for a 60-day period as drinking water; controls received only ordinary water.
D. J. Mewissen, C. L. Comar
core   +1 more source

Relative Value of Cysteamine and Cystamine as Radioprotective Agents for Fetal and Adult Mice

, 1957
The —SH compound cysteamine and its —SS product, cystamine, have been tested as protective agents against x-irradiation death for adult CF1 mice of both sexes, and also the 15.5–17.5-day fetuses of the same strain.
Roberts Rugh
core   +1 more source

Cystamine inhibits the amidolytic activity of coagulation enzymes.

, 2015
Factors IXa (circles), Xa (squares), VIIa (diamonds), XIa (triangles), and thrombin (inverted triangles) amidolytic activity were assayed by incubating enzymes with cystamine (A) or T101 (B) and measuring the cleavage rate of chromogenic substrates.
Maria M. Aleman (730511), Christa I. Devette (730513), Lori A. Holle (730512), Dougald M. Monroe (730514), Katherine G. Stember (647428), Alisa S. Wolberg (695929)   +5 more
core   +1 more source

Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR

, 2013
Cystic fibrosis (CF) is most frequently due to homozygous ΔF508-CFTR mutation. The ΔF508-CFTR protein is unstable in the plasma membrane (PM), even if it is rescued by pharmacological agents that prevent its intracellular retention and degradation ...
RAIA, VALERIA, VILLELLA, VALERIA RACHELA, ESPOSITO, SPERANZA, MAIURI, MARIA CHIARA, MAIURI, Luigi, Villella, Valeria R, Guido Kroemer, Luigi Maiuri, Kroemer, Guido   +8 more
core   +1 more source

Influence of rat blood on radiation protection of mammalian cells by cysteamine and cystamine in vitro

, 1975
The protective effect of cystamine and cystamine on T-cells in normal growth-medium was studied in the presence of whole rate blood (WRB). The protective effectiveness of both agents was increased by the addition of WRB, but much less so on the activity ...
Budke, L., Vos, O., Grant, G.A.
core  

Improving Lettuce Tolerance to Cadmium Stress: Insights from Raw vs. Cystamine-Modified Biochar

Horticulturae
Understanding the interactions among biochar, plants, soils, and microbial communities is essential for developing effective and eco-friendly soil remediation strategies.
Rongqi Chen, Xi Duan, Ruoxuan Xu, Tao Zhao   +3 more
doaj   +1 more source