Results 71 to 80 of about 4,936 (212)
<i>Background:</i> Tissue transglutaminase (t-TG) has been implicated in small artery remodelling. The aim of this study was to determine if cystamine, an inhibitor of t-TG, could reduce blood pressure in spontaneously hypertensive rats (SHR)
E. Bald +4 more
core +1 more source
Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice [PDF]
[[abstract]]Increased hepatic abnormality has been observed in patients with systemic lupus erythematosus (SLE) and contributes to the elevated apoptosis that results in severe disease activity.
Hsu, TC (Hsu, Tsai-Ching); Huang, CY (Huang, Chih-Yang); Chiang, SY (Chiang, Szu-Yi); Lai, WX (Lai, Wen-Xian); Tsai, CH (Tsai, Chang-Hai); Tzang, BS (Tzang, Bor-Show)
core
Cystamine has shown significant neuroprotective properties in preclinical studies of Parkinson’s disease (PD) and Huntington’s disease (HD). Cysteamine, its FDA-approved reduced form, is scheduled to be tested for clinical efficacy in HD patients.
Gibrat, Claire +5 more
core +1 more source
Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. [PDF]
Reaction between cysteamine (systematic name: 2-aminoethanethiol, C 2H7NS) and l-(+)-tartaric acid [systematic name: (2R,3R)-2,3-dihydroxybutanedioic acid, C4H6O6] results in a mixture of cysteamine tartrate(1-) monohydrate, C2H 8NS+·C4H5O6-·H2O, (I ...
Cairns, Donald +3 more
core +1 more source
Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao +5 more
wiley +1 more source
We have investigated the effects of cystamine on the replication of human immunodeficiency virus (HIV) in human lymphocytes and macrophages, the natural targets of HIV in vivo.
S Beninati +57 more
core +1 more source
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +1 more source
Alzheimer’s disease (AD) is a complex neurodegenerative disease that can lead to the loss of cognitive function. The progression of AD is regulated by multiple signaling pathways and their associated targets.
Xiuyuan Wu +8 more
doaj +1 more source
Stimuli Response of Cystamine-Core Dendrimer Revealed by Diffusion and NOE NMR Studies
Stimuli response behaviors of cystamine-core dendrimer in the presence of several reducing agents including vitamin C, sodium bisulfite, and dl-Dithiothreitol are described.
Xueyan Feng (1750483) +4 more
core +1 more source
Cutting fluid wastewater contains a large amount of emulsified oil. If it is discharged directly without treatment, it will cause environmental pollution and water ecosystem destruction.
LIU Yaowei +5 more
doaj +1 more source

