Results 71 to 80 of about 4,936 (212)

Effect of Cystamine on Blood Pressure and Vascular Characteristics in Spontaneously Hypertensive Rats

open access: yes, 2011
<i>Background:</i> Tissue transglutaminase (t-TG) has been implicated in small artery remodelling. The aim of this study was to determine if cystamine, an inhibitor of t-TG, could reduce blood pressure in spontaneously hypertensive rats (SHR)
E. Bald   +4 more
core   +1 more source

Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice [PDF]

open access: yes, 2010
[[abstract]]Increased hepatic abnormality has been observed in patients with systemic lupus erythematosus (SLE) and contributes to the elevated apoptosis that results in severe disease activity.
Hsu, TC (Hsu, Tsai-Ching); Huang, CY (Huang, Chih-Yang); Chiang, SY (Chiang, Szu-Yi); Lai, WX (Lai, Wen-Xian); Tsai, CH (Tsai, Chang-Hai); Tzang, BS (Tzang, Bor-Show)
core  

Cystamine metabolism and brain transport properties : clinical implications for neurodegenerative diseases

open access: yes, 2010
Cystamine has shown significant neuroprotective properties in preclinical studies of Parkinson’s disease (PD) and Huntington’s disease (HD). Cysteamine, its FDA-approved reduced form, is scheduled to be tested for clinical efficacy in HD patients.
Gibrat, Claire   +5 more
core   +1 more source

Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. [PDF]

open access: yes, 2013
Reaction between cysteamine (systematic name: 2-aminoethanethiol, C 2H7NS) and l-(+)-tartaric acid [systematic name: (2R,3R)-2,3-dihydroxybutanedioic acid, C4H6O6] results in a mixture of cysteamine tartrate(1-) monohydrate, C2H 8NS+·C4H5O6-·H2O, (I ...
Cairns, Donald   +3 more
core   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao   +5 more
wiley   +1 more source

Cystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cells

open access: yes, 1994
We have investigated the effects of cystamine on the replication of human immunodeficiency virus (HIV) in human lymphocytes and macrophages, the natural targets of HIV in vivo.
S Beninati   +57 more
core   +1 more source

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer’s Disease

open access: yesMolecules
Alzheimer’s disease (AD) is a complex neurodegenerative disease that can lead to the loss of cognitive function. The progression of AD is regulated by multiple signaling pathways and their associated targets.
Xiuyuan Wu   +8 more
doaj   +1 more source

Stimuli Response of Cystamine-Core Dendrimer Revealed by Diffusion and NOE NMR Studies

open access: yes, 2016
Stimuli response behaviors of cystamine-core dendrimer in the presence of several reducing agents including vitamin C, sodium bisulfite, and dl-Dithiothreitol are described.
Xueyan Feng (1750483)   +4 more
core   +1 more source

Preparation of PVDF-based ultrafiltration membranes and its wastewater separation properties of cutting fluid

open access: yesCailiao gongcheng
Cutting fluid wastewater contains a large amount of emulsified oil. If it is discharged directly without treatment, it will cause environmental pollution and water ecosystem destruction.
LIU Yaowei   +5 more
doaj   +1 more source

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