Results 21 to 30 of about 6,537 (217)

Cystamine reduces vascular stiffness in Western diet-fed female mice.

American Journal of Physiology. Heart and Circulatory Physiology, 2021
Consumption of diets high in fat, sugar and salt (Western diet, WD) is associated with accelerated arterial stiffening, a major independent risk factor for cardiovascular disease (CVD). Obese women are more prone to develop arterial stiffening leading to
Francisco I. Ramirez-Perez, Francisco J. Cabral-Amador, A. Whaley-Connell, A. Aroor, Mariana Morales‐Quinones, Makenzie L. Woodford, Thaysa Ghiarone, Larissa Ferreira-Santos, T. Jurrissen, Camila Manrique-Acevedo, Guanghong Jia, V. DeMarco, J. Padilla, Luis A. Martinez‐Lemus, G. Lastra   +14 more
semanticscholar   +1 more source

N,N-Bis(7-nitrobenz[c][1,2,5]oxadiazol-4-yl)cystamine

Molbank, 2022
Background: New amino derivatives of NBD type are of high interest due to their strong fluorescence, while compounds containing a disulphide moiety are of high interest in nano-chemistry due to their easiness of attaching to noble nanoparticles ...
Iulia Matei, Dana C. Culita, Victorita Tecuceanu, Anamaria Hanganu, Petre Ionita   +4 more
doaj   +1 more source

Inhibiting Transglutaminase 2 Mediates Kidney Fibrosis via Anti-Apoptosis

Biomedicines, 2022
Transglutaminase 2 (TG2) is a calcium-dependent transamidating acyltransferase enzyme of the protein-glutamine γ-glutamyltransferase family implicated in kidney injury. In this study, we identified associations between TG2 and chronic kidney disease (CKD)
Jong-Joo Moon, Yejin Choi, Kyu-Hyeon Kim, Areum Seo, Soie Kwon, Yong-Chul Kim, Dong-Ki Kim, Yon-Su Kim, Seung-Hee Yang   +8 more
doaj   +1 more source

Combining Dextran Conjugates with Stimuli-Responsive and Folate-Targeting Activity: A New Class of Multifunctional Nanoparticles for Cancer Therapy

Nanomaterials, 2021
Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs.
Manuela Curcio, Alessandro Paolì, Giuseppe Cirillo, Sebastiano Di Pietro, Martina Forestiero, Francesca Giordano, Loredana Mauro, Diana Amantea, Valeria Di Bussolo, Fiore Pasquale Nicoletta, Francesca Iemma   +10 more
doaj   +1 more source

Cystamine Improves Functional Recovery via Axon Remodeling and Neuroprotection after Stroke in Mice

CNS Neuroscience and Therapeutics, 2015
Gao-Jun Teng, Jie Ding, Ying Cui
exaly   +2 more sources

Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease

Neurobiology of Disease, 2015
The neuroprotective properties of cystamine identified in pre-clinical studies have fast-tracked this compound to clinical trials in Huntington's disease, showing tolerability and benefits on motor symptoms.
G. Cisbani, J. Drouin-Ouellet, C. Gibrat, M. Saint-Pierre, M. Lagacé, S. Badrinarayanan, M.H. Lavallée-Bourget, J. Charest, A. Chabrat, L. Boivin, M. Lebel, M. Bousquet, M. Lévesque, F. Cicchetti   +13 more
doaj   +1 more source

Facile synthesis of redox-responsive paclitaxel drug release platform using metal-organic frameworks (ZIF-8) for gastric cancer treatment

Materials Research Express, 2020
This paper investigated the dual-role of cystamine as a surface modification linker and stimuli-responsive material, and simplify redox-responsive drug delivery system synthesis.
Aiqing Ma, Rui Zhang
doaj   +1 more source

Cysteamine as a novel disease-modifying compound for Parkinson's disease: Over a decade of research supporting a clinical trial

Neurobiology of Disease, 2019
To date, medical and surgical interventions offered to patients with Parkinson's disease (PD) serve only to manage clinical symptoms; they have not shown the capacity to halt nor reverse degenerative processes.
F. Cicchetti, L.S. David, A. Siddu, H.L. Denis   +3 more
doaj   +1 more source

Osteolathyrogenic Action of Mercaptoethylamine and of Cystamine.

Experimental Biology and Medicine, 1958
SummaryThe osteolathyrogenic action of β-mercaptoethylamine (cysteamine), when fed to rats as the hydrochloride, was confirmed. Cystamine was found to have similar properties. Gross and microscopic skeletal changes were similar to those produced by osteolathyrogenic nitriles.
W, DASLER, R V, MILLISER
openaire   +2 more sources

The interaction of cystamine with bovine brain tubulin [PDF]

European Journal of Biochemistry, 1987
Microtubule assembly in vitro is sensitive to a variety of non‐physiological sulfhydryl‐oxidizing agents, but the physiological significance of this phenomenon is unknown, since no physiological sulfhydryl‐oxidizing agent has been shown to affect microtubule assembly in vitro.
A, Banerjee, M A, Jordan, M, Little, R F, Luduena   +3 more
openaire   +2 more sources