Results 21 to 30 of about 4,936 (212)
Nanomaterials, 2021 Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs.
Manuela Curcio +10 more
doaj +1 more source
Cystamine induces AIF-mediated apoptosis through glutathione depletion [PDF]
, 2015 Cystamine and its reduced form cysteamine showed protective effects in various models of neurodegenerative disease, including Huntington's disease and Parkinson's disease.
Kim, Hyo-Jun +12 more
core +1 more source
Materials Research Express, 2020 This paper investigated the dual-role of cystamine as a surface modification linker and stimuli-responsive material, and simplify redox-responsive drug delivery system synthesis.
Aiqing Ma, Rui Zhang
doaj +1 more source
Iodometric determination of cystamine dihydrochloride in tablets using diperoxyadipic acid [PDF]
, 2020 The kinetics of cystamine dihydrochloride oxidation by diperoxyadipic acid (DPAA) was studied in aqueous buffer solutions of pH 2.9, 6.9, 8.0, 8.5 and 9.2 under second-order conditions at the temperature 293 K. The second order rate constants, k (L mol−1
Blazheyevskiy, Mykola, Moroz, Valeriy
core +1 more source
Total Chemical Synthesis of Interleukin-15 and Interleukin-2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy. [PDF]
Angew Chem Int Ed EnglA reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Zeng J, Zhou H, Xia W, Wu H, Li X.
europepmc +3 more sources
Osteolathyrogenic Action of Mercaptoethylamine and of Cystamine.
Experimental Biology and Medicine, 1958 SummaryThe osteolathyrogenic action of β-mercaptoethylamine (cysteamine), when fed to rats as the hydrochloride, was confirmed. Cystamine was found to have similar properties. Gross and microscopic skeletal changes were similar to those produced by osteolathyrogenic nitriles.
W, DASLER, R V, MILLISER
openaire +2 more sources
Frontiers in Neurology, 2019 Current medications for neurodegenerative and neuropsychiatric diseases such as Alzheimer's disease (AD), Huntington's disease (HD), Parkinson's disease (PD), and Schizophrenia mainly target disease symptoms.
Bindu D. Paul +3 more
doaj +1 more source
Soft Hardware, Flowing Software: Reconfigurable Microfluidics for Adaptable Chemical Computation. [PDF]
Adv MaterA reconfigurable microfluidic platform based on soft, photo‐printable, and chemically erasable hydrogel structures printed and erased in situ is used to control flow routing, mixing, chemical patterning, and even chemical computing. Using hardware to control chemical computations decouples logic function from molecular composition, demonstrated via ...
Swinkels PJM +4 more
europepmc +2 more sources
Neurobiology of Disease, 2019 To date, medical and surgical interventions offered to patients with Parkinson's disease (PD) serve only to manage clinical symptoms; they have not shown the capacity to halt nor reverse degenerative processes.
F. Cicchetti +3 more
doaj +1 more source
Inhibition of melanin synthesis by cystamine in human melanoma cells [PDF]
, 2000 In studies to determine whether pigmentation can be regulated physiologically by thiols, human melanoma cells (MM418c5) and melanocytes were found to become depigmented when cultured continuously in 50 mu M cystamine.
Brooke Gardiner +20 more
core +1 more source