Results 11 to 20 of about 6,537 (217)
Molecular Hydrogen as an Antioxidant and Radioprotector: Mechanistic Insights from Monte Carlo Radiation-Chemical Simulations [PDF]
Antioxidants(1) Background: Water, comprising about 70–80% of cellular mass, is the most abundant constituent of living cells. Upon exposure to ionizing radiation, water undergoes radiolysis, generating a variety of reactive species, including free radicals and ...
Sumaiya Akhter Ria +2 more
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Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with DNAJB2/HSJ1 Mutation: Cystamine as a Potential Therapeutic Intervention [PDF]
Neurology InternationalBackground and Objectives: Neuropathy is a debilitating disorder characterized by peripheral nerve dysfunction and damage to sensory, motor, and autonomic neurons and their axons.
Raj Kumar Pradhan +3 more
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New Ibuprofen Cystamine Salts With Improved Solubility and Anti‐Inflammatory Effect [PDF]
ChemistryOpenTwo novel ibuprofen cystamine salts (IBU‐CYS 1 and IBU‐CYS 2) are synthesized by coupling the anion of ibuprofen with cystamine dihydrochloride in 1 : 1 and 2 : 1 ratio to improve the solubility and bioavailability of ibuprofen.
Simay Denizkusu +3 more
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APL Materials, 2018 We have synthesized and studied a specific family of disulfide bridge based 2D organic inorganic hybrid perovskites using the cation, cystamine [2,2′-dithiobis(ethylammonium), abbreviated as SS] in the three lead halide (X = I, Br, and Cl) based systems,
Shrreya Krishnamurthy +5 more
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A Novel HDAC6 Inhibitor Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice [PDF]
MoleculesPsoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation of keratinocytes and infiltration of inflammatory cells. Significant challenges remain in developing effective and safe targeted therapies for psoriasis.
Anqi Cao +6 more
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Vanillin-Based Epoxy Vitrimers: Looking at the Cystamine Hardener from a Different Perspective
ACS Sustainable Chemistry and Engineering, 2023 Epoxy vitrimers encompass many advantages compared to traditional epoxy materials such as recyclability, repairability, and reprocessability. These properties are induced by the incorporation of dynamic reversible covalent bonds.
Solène Guggari +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2023 Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria.
I. Palucci +12 more
semanticscholar +1 more source
Cells, 2021 The ongoing pandemic of coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), needs better treatment options both at antiviral and anti-inflammatory levels.
Tonino Alonzi +13 more
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Enzymatic and non-enzymatic conversion of cystamine to thiotaurine and taurine
Biochimica et Biophysica Acta - General Subjects, 2022 The disulfide-containing molecule cystamine and the thiosulfonate thiotaurine are of interest as therapeutics. Both are precursors of taurine, but the chemistry of their metabolism is not clear.
Steven J. Karpowicz, L. Anderson
semanticscholar +1 more source
Frontiers in Immunology, 2020 Host-directed therapies (HDTs) are emerging as a potential valid support in the treatment of drug-resistant tuberculosis (TB). Following our recent report indicating that genetic and pharmacological inhibition of transglutaminase 2 (TG2) restricts ...
Ivana Palucci +21 more
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