Results 11 to 20 of about 4,936 (212)
Cystamine preparations exhibit anticoagulant activity. [PDF]
PLoS ONE, 2015 Transglutaminases are a superfamily of isoenzymes found in cells and plasma. These enzymes catalyze the formation of ε-N-(γ-glutamyl)-lysyl crosslinks between proteins.
Maria M Aleman +5 more
doaj +5 more sources
N,N-Bis(7-nitrobenz[c][1,2,5]oxadiazol-4-yl)cystamine
Molbank, 2022 Background: New amino derivatives of NBD type are of high interest due to their strong fluorescence, while compounds containing a disulphide moiety are of high interest in nano-chemistry due to their easiness of attaching to noble nanoparticles ...
Iulia Matei +4 more
doaj +2 more sources
Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease [PDF]
Neurobiology of Disease, 2015 The neuroprotective properties of cystamine identified in pre-clinical studies have fast-tracked this compound to clinical trials in Huntington's disease, showing tolerability and benefits on motor symptoms.
G. Cisbani +13 more
doaj +2 more sources
Synthesis and Characterization of Healable Waterborne Polyurethanes with Cystamine Chain Extenders
Molecules, 2019 In this study, environmentally friendly, self-healing waterborne polyurethanes (WPUs) were prepared based on the disulfide metathesis reaction in cystamine.
Dae-Il Lee, Seung-Hyun Kim, Dai-Soo Lee
doaj +2 more sources
Pharmaceutics, 2020 Cystamine-based polymers may help to achieve controlled and targeted drug delivery to the colon due to their susceptibility to breakage of the disulfide linkage in the low redox potential environment of the colon.
Yoke Mooi Ng +3 more
doaj +2 more sources
International Journal of Nanomedicine, 2010 Rongzuo Xu1, Todd Lyle Kaneshiro1, Eun-Kee Jeong2, Dennis L Parker2, Zheng-Rong Lu31Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, USA; 2Department of Radiology, University of Utah, Salt Lake City, UT ...
Rongzuo Xu +3 more
doaj +1 more source
Inhibiting Transglutaminase 2 Mediates Kidney Fibrosis via Anti-Apoptosis
Biomedicines, 2022 Transglutaminase 2 (TG2) is a calcium-dependent transamidating acyltransferase enzyme of the protein-glutamine γ-glutamyltransferase family implicated in kidney injury. In this study, we identified associations between TG2 and chronic kidney disease (CKD)
Jong-Joo Moon +8 more
doaj +1 more source
CYSTAMINE TREATMENT OF CHEMICALLY-INDUCED HEPATOTOXICITY
, 1984 There are few examples of therapeutic treatments in chemically-induced toxicity compared to pretreatments that protect against chemical injury. Cystamine treatment 12 hours after carbon tetrachloride (CCl₄) was reported to have therapeutic effects on ...
MACDONALD, JOHN ROBERT.
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Effect of Cystamine on Sperm and Antioxidant Parameters of Ram Semen Stored at 4 °C for 50 Hours [PDF]
Archives of Razi Institute, 2021 Physical and chemical changes caused by oxidative stress in the spermatozoa membrane can reduce spermatozoa function and even lead to death. Cystamine (NH2-CH2-CH2-SH, β-mercaptoethylamine) is a natural substance that modulates the endocrine and ...
J Jumintono +9 more
doaj +1 more source
Cysteamine/Cystamine Exert Anti-Mycobacterium abscessus Activity Alone or in Combination with Amikacin [PDF]
, 2023 Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria.
Delogu, Giovanni +25 more
core +3 more sources