Results 101 to 110 of about 12,194 (220)

Synaptobrevin‐2 Containing Extracellular Vesicles Are Rapidly Incorporated Into Mammalian Neurons via a Dynamin‐Dependent Pathway

Journal of Neurochemistry, Volume 170, Issue 9, September 2026.
In this article, Hannett and colleagues investigate extracellular vesicles (EVs) secreted by neurons, small membrane‐bound organelles that transmit information among cells. They found that EVs are mainly uptaken by target neurons via a mechanism dependent on the membrane scission protein Dynamin.
Victoria Hannett, A. Alejandro Vilcaes, Siewert Hugelier, Qing Tang, Melike Lakadamyali, Natali L. Chanaday   +5 more
wiley   +1 more source

Copper deficiency in patients with cystinosis with cysteamine toxicity

, 2013
Item does not contain fulltextOBJECTIVES: To assess whether copper deficiency plays a role in the recently described cysteamine toxicity in patients with cystinosis, and to examine whether polymorphisms in copper transporters, lysyl oxidase, and/or type ...
Lillen, Marc R, Heuvel, L.P.W.J. van den, Malfait, Fransiska, Lilien, M.R., Besouw, Martine T, De Paepe, Anne, Lilien, Marc R., Emma, Francesco, van den Heuvel, Lambertus P., Symoens, Sofie, Janssen, Mirian C., Janssen, M.C.H., Nobili, F., Emma, F., Skovby, Flemming, Besouw, Martine T P, Greco, Marcella, Desmet, K., Symoens, S., Janssen, Mirian C, Schneider, Jerry, Schneider, J., Besouw, M.T., Lilien, Marc R, Greco, M., Malfait, F., Cornelissen, Elisabeth A, Levtchenko, Elena N, Paepe, A. de, Skovby, F., van den Heuvel, Lambertus P, Levtchenko, E.N., Nobili, François, Cornelissen, Elisabeth A., Desmet, Koen, Besouw, Martine T. P., Cornelissen, E.A.M., Levtchenko, Elena N.   +37 more
core   +1 more source

The mechanism of gastrin release in cysteamine-induced duodenal ulcer

, 1982
Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels.
Poulsen, Steen Seier
core   +1 more source

Adherence to Cysteamine Therapy Among Patients Diagnosed with Cystinosis in Saudi Arabia: A Prospective Cohort Study

Pharmacy
Cystinosis is a rare autosomal recessive disorder in which cystine crystals accumulate within the cellular lysosomes, causing damage to multiple organs.
Reem Algasem, Nedaa Zainy, Essam Alsabban, Hamad Almojalli, Khalid Alhasan, Tariq Ali, Deiter Broering, Hassan Aleid   +7 more
doaj   +1 more source

Antioxidant effect of cysteamine in brain cortex of young rats

, 2008
Cysteamine is a cystine-depleting drug used in the treatment of cystinosis, a metabolic disorder caused by deficiency of the lysosomal cystine carrier.
Biasibetti, Micheli, Kessler, Adriana, Wannmacher, Clovis Milton Duval, Wyse, Angela Terezinha de Souza, Wajner, Moacir, Melo, Denizar Alberto da Silva, Dutra Filho, Carlos Severo   +6 more
core   +1 more source

The protective effects of cysteamine, putrescine, and the combination of cysteamine and putrescine on fibrosarcoma induced in mice with 3-methylcholanthrene

, 2016
In this study, the protective effects of cysteamine, putrescine, and the combination of cysteamine and putrescine were investigated in mice with fibrosarcoma induced with 3-methylcholanthrene (3-MC).
Erdağ D., Kiliçle P.A., Doğan, Abdullah, Doğan, Ertan, Doğan E., Erdağ, Dinçer, özcan K., Kiliçle, Pinar Aksu, Doğan A., Özcan, Kadir, Doğan A.N.C., Doğan, Ali Nazmi Can   +11 more
core   +1 more source

Effect of cysteamine on serum enzymes and creatinine levels.

, 2012
Tumor bearing mice were treated with increasing doses of cysteamine and serum was collected from tail veins twice, i.e., pre-cysteamine treatment (day 4) and post- treatment (day 18).
Benjamin Rubin (169516), Bharat H. Joshi (169537), Prabhudas S. Patel (169529), Raj K. Puri (169540), Akiko Suzuki (169522), Toshio Fujisawa (169513), William A. Gahl (169534)   +6 more
core   +1 more source

Comparison between the efficacy of cysteamine cream and combined hydroquinone cream in the treatment of melasma using skin analytical systems: An open-label quasi-randomized controlled trial in Asia patients

Dermatologica Sinica
Background: The mainstay of treatment for melasma is topical hydroquinone or preparations containing hydroquinone. In recent years, cysteamine cream has gained popularity in the treatment of hyperpigmentation disorders.
Andy Deng-Chi Chuang, Erh-Ti Lin, Chang-Cheng Chang, Yung-Hsueh Huang, Meng-En Lu, Chun-Fang Chuang, Hsiu-Mei Chiang   +6 more
doaj   +1 more source

Efficacy and safety of cysteamine in the treatment of melasma: a systematic review and meta-analysis of randomized controlled trials

Journal of the Egyptian Women’s Dermatologic Society
Melasma is a persistent and recurrent pigmentation disorder that significantly impacts patients’ quality of life and presents challenges in management with conventional treatments.
Monica Trifitriana, Yuli Kurniawati, Fatima A. Khairani   +2 more
doaj   +1 more source

Prolonged release pharmaceutical composition comprising cysteamine or salt thereof

, 2021
A prolonged release multiple unit dosage form, preferably pellets, of cysteamine, cystamine or a pharmaceutically acceptable salt thereof, preferably cysteamine bitartrate, with a non gastro-resistant coating is described. The dosage form is particularly
A. Maroni, M. Barchielli, A. Gazzaniga, M. Cerea   +3 more
core   +1 more source