Results 131 to 140 of about 8,396 (186)

Treatment of cystinosis with cysteamine

The Journal of Pediatrics, 1979
C v s T I N 0 S I S is a recessively inherited metabolic disorder characterized by an accumulation of nonprotein cystine within the lysosomes. 1 ! n the juvenile nephropathic form, the disease presents with tubular renal dysfunction and progressive glomerular damage, leading to end-stage renal failure and eventual death.
E P, Girardin, M S, DeWolfe, J F, Crocker   +2 more
openaire   +2 more sources

Cysteamine Toxicity in Patients with Cystinosis

The Journal of Pediatrics, 2011
To report new adverse effects of cysteamine.Detailed clinical information was obtained from the patients' physicians.New adverse events were reported in 8 of 550 patients with cystinosis treated with cysteamine in Europe during the last 5 years. Detailed clinical information was not available for 2 of these patients, 1 of whom died from cerebral ...
Besouw, M.T., Bowker, R., Dutertre, J.P., Emma, F., Gahl, W.A., Greco, M., Lilien, M.R., McKiernan, J., Nobili, F., Schneider, J.A., Skovby, F., van den Heuvel, L.P., van den Heuvel, L.P., van 't Hoff, W.G., Levtchenko, E.N.   +14 more
openaire   +5 more sources

Metal Content of Cysteamine Oxygenase

European Journal of Biochemistry, 1968
Cysteamine oxygenase has been analysed for the presence of metals, by spectrographic analysis, and X‐ray fluorescence. Iron, copper, and zinc have been found in the enzyme in the quantity accounting for 1 atom of each metal per molecule of enzyme.Passage of the enzyme through a chelating resin column did not appreciable change the specific activity but
D, Cavallini, S, Duprè, R, Scandurra, M T, Graziani, F, Cotta-Rasusino   +4 more
openaire   +2 more sources

Cysteamine

Drug Discovery Today, 2013
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis, in which cysteamine is prescribed to decrease intralysosomal cystine ...
Besouw, Martine, Masereeuw, R., van den Heuvel, Lambert, Levtchenko, Elena   +3 more
openaire   +2 more sources

Adrenergic blocking action of cysteamine

Experientia, 1962
Il a ete demontre que la cysteamine provoque une activation centrale adrenergique accompagnee par une liberation des catecholamines de la surrenale. Plus tard cet effet est suivi par un blocage periferique des recepteurs adrenergiques.
R, DEBIJADJI, V, VARAGIC, S, ELCIC, J, DAVIDOVIC   +3 more
openaire   +2 more sources

Radiation Protection of Tissue Culture Cells by Anoxia, Cysteamine and a Combination of Anoxia and Cysteamine

Nature, 1962
Evidence is given in support of the hypothesis that the radioprotective action of a group of sulfhydryl compounds such as cysteine and cysteamine is not based on the removal of oxygen but is caused by another mode of action on the cellular level. In the experiments, cysteamine in concentrations of 4 and 16 mM- bar gave dose reduction factors of 1.8 and
A J, VERGROESEN, O, VOS, L, BUDKE
openaire   +2 more sources

Effects of cysteamine on nociception in mice.

Acta pharmacologica Sinica, 2001
The present study was carried to study the effects of cysteamine on nociception in mice.The pain assays were the hot plate and the tail flick test.When cysteamine, a drug well known as a somatostatin depletor, was administered 1 and 4 but not 24 h before the tests (hot plate, tail flick), the nociceptive threshold was elevated when the drug was ...
CAPASSO, Anna, A. LOIZZO
openaire   +2 more sources

METABOLISM OF CYSTEAMINE

The Journal of Pharmacology and Experimental Therapeutics, 1957
R A, SALVADOR, C, DAVISON, P K, SMITH
openaire   +2 more sources

Cysteamine dioxygenase

1987
R B, Richerson, D M, Ziegler
openaire   +2 more sources

A sensitive “off-on” carbon dots-Ag nanoparticles fluorescent probe for cysteamine detection via the inner filter effect

Talanta, 2021
Yibing Huang, Xinpei Li, Daqian Song
exaly