Results 21 to 30 of about 11,095 (222)
Orphanet Journal of Rare Diseases, 2022 Background To date, measurement of intracellular cystine is used for the therapeutic monitoring of patients affected by cystinosis in treatment with cysteamine.
Martina Franzin +6 more
doaj +1 more source
Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs
Animals, 2021 This study aimed to explore the effects of dietary coated cysteamine on oxidative stress and inflammation in diquat-induced weaning pigs. Twenty-four pigs were randomly assigned to three dietary groups with eight replicates: the control (fed base diet ...
Shanshan Wang +8 more
doaj +1 more source
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation [PDF]
, 2014 Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures
Salvadori L +112 more
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Effect of cysteamine and 13-cis-retinoic acid on bovine in vitro embryo production [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018 One of the main factors decreasing the success of an in vitro embryo production is oxidative stress-mediated reactive oxygen species resulting in cellular damages.
Abdolreza RANJBAR +2 more
doaj +1 more source
Investigation Of A Novel Mammalian Thiol Dioxygenase Structure: Human Cysteamine Dioxygenase [PDF]
, 2018 In 2007, a gene homolog of CDO encoded by the gene Gm237 in the DUF164 family was identified as cysteamine dioxygenase (ADO). ADO is one of the only known thiol dioxygenases found in mammals.
Xiong, Tseng
core +1 more source
Ophthalmology and Therapy, 2019 Introduction Treatment of the anterior segment problems in cystinosis is challenging as oral cysteamine is ineffective in the treatment of corneal problems because of its avascular structure.
Freya Peeters +5 more
doaj +1 more source
Effect of cysteamine on mutant ASL proteins with cysteine for arginine substitutions [PDF]
, 2016 INTRODUCTION Cysteamine is used to treat cystinosis via the modification of cysteine residues substituting arginine in mutant proteins. OBJECTIVES We investigated the effect of cysteamine on mutant argininosuccinate lyase (ASL), the second most common ...
Rüfenacht, Véronique +9 more
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Cysteamine activation of ELIC. [PDF]
, 2013 Outside-out patch-clamp recordings from HEK-293T cells expressing ELIC. ELIC currents evoked by alternating pulses of 30 mM and 10 mM or 50 mM cysteamine (black bar) are overlaid.
Borna Ghosh (486869) +2 more
core +1 more source
Improved method for the preparation of malonyl coenzyme A
Journal of Lipid Research, 1968 Malonyl coenzyme A is synthesized by transacylating S-malonyl-N-decanoyl cysteamine with coenzyme A. A simplified procedure for the preparation of S-malonyl-N-decanoyl cysteamine, using cysteamine as starting material, is described.
Hans Mohrhauer +4 more
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Cysteamine: an old drug with new potential [PDF]
, 2013 Item does not contain fulltextCysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low.
Levtchenko, Elena +7 more
core +1 more source