Results 81 to 90 of about 12,194 (220)

Cognitive functions and behavioural profiles in children with cystinosis treated with cysteamine and correlation with treatment duration

open access: yesMiddle East Current Psychiatry, 2022
Background Cystinosis is a rare autosomal recessive disease. Children with nephropathic cystinosis (NCTN) have evidence of intellectual dysfunction and behavioural abnormalities which are attributed to renal dysfunction, metabolic disarrangement, and ...
Fatma M. Atia   +3 more
doaj   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

open access: yesVIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi   +5 more
wiley   +1 more source

Effect of melatonin and/or cysteamine on development and vitrification of buffalo embryos

open access: yesAsian Pacific Journal of Reproduction, 2017
Objective: To assess the effects of melatonin and/or cysteamineon in vitro maturation, culturing and post-warming of buffalo embryos.Methods: Buffalo oocytes were classified into control, cysteamine (50 μM), melatonin (10 ng/mL) and cysteamine (50 μM ...
Mohamed MM El-Sokary   +4 more
doaj   +1 more source

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

open access: yesInternational Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar   +12 more
wiley   +1 more source

Conformational ensembles of the disordered 4E‐BP2:eIF4E complex restrained by smFRET experiments

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Eukaryotic cap‐dependent translation initiation is regulated by binding of the predominantly folded eukaryotic initiation factor 4E (eIF4E) to the intrinsically disordered eIF4E binding proteins (4E‐BPs). Here, we report full‐length atomistic conformational ensembles generated by IDPConformerGenerator and optimized by X‐EISDv2 workflow for ...
Spencer Smyth   +5 more
wiley   +1 more source

Enteric-Coated Cysteamine Bitartrate in Cystinosis Patients

open access: yes
Cystinosis is a severe inherited metabolic storage disease caused by the lysosomal accumulation of cystine. Lifelong therapy with the drug cysteamine bitartrate is necessary. Cysteamine cleaves intralysosomal cystine, and thereafter, it can exit from the
Rauwolf, K.K. (Kerstin)   +8 more
core   +1 more source

Cysteamine functionalised reduced graphene oxide modification of maleated poly(propylene) [PDF]

open access: yes, 2020
Graphene oxide (GO) was reduced (rGO) and then functionalised with an amino terminated thiol molecule (cysteamine) via a thiol-ene click chemistry reaction to produce reduced graphene oxide-cysteamine (rGO-cyst). The presence of the C–S bond in the X-ray
Abbas, Syeda   +4 more
core   +1 more source

Cysteamine prevents vascular leakage through inhibiting transglutaminase in diabetic retina

open access: yes, 2017
Cysteamine (an aminothiol), which is derived from coenzyme A degradation and metabolized into taurine, has beneficial effects against cystinosis and neurodegenerative diseases; however, its role in diabetic complications is unknown.
Seok-Ho Hong   +8 more
core   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

open access: yesAdvanced Functional Materials, Volume 36, Issue 71, 3 September 2026.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández   +14 more
wiley   +1 more source

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy