Results 91 to 100 of about 12,194 (220)

Cystamine and Cysteamine As Inhibitors of Transglutaminases In Vivo [PDF]

open access: yes, 2018
Cystamine is commonly used as a transglutaminase inhibitor. This disulfide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either ...
Jeitner, Thomas M   +2 more
core   +1 more source

Brunner's glands of the rat during cysteamine ulceration

open access: yes, 1981
Duodenal ulcers can be produced in rats by subcutaneous administration of cysteamine-HCl. The pathogenesis of these ulcers has not been fully explained. Increased acid secretion is necessary but not sufficient for ulcer production.
Poulsen, Steen Seier
core   +1 more source

Influence of supplemented coated-cysteamine on morphology, apoptosis and oxidative stress status of gastrointestinal tract

open access: yesBMC Veterinary Research, 2019
Background Cysteamine was coated to cover its odor and maintain the stability. However, coated cysteamine (CC) has not been clearly evaluated for its effects on the gastrointestinal mucosa status. We hypothesize that the appropriate CC supplementation in
Hongnan Liu   +6 more
doaj   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 9, September 2026.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley   +1 more source

Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone

open access: yes, 2001
Recently, we showed cysteamine-duodenal lesions without gastric acid, since they were induced also in gastrectomized rats, as in naive rats, and they were inhibited by the novel stomach pentadecapeptide BPC 157 as well as standard antiulcer drugs (i.e ...
Sven Seiwerth   +27 more
core   +1 more source

A New and Rapid LC-MS/MS Method for the Determination of Cysteamine Plasma Levels in Cystinosis Patients

open access: yesPharmaceuticals
Cystinosis is a rare lysosomal storage disorder caused by autosomal recessive mutations in the CTNS gene that encodes for the cystine transporter cystinosin, which is expressed on the lysosomal membrane mediating the efflux of cystine.
Raffaele Simeoli   +8 more
doaj   +1 more source

Synthesis and Characterization of a Cationic Thiomer Based on Ethyl Cellulose for Realization of Mucoadhesive Tablets and Nanoparticles

open access: yesInternational Journal of Nanomedicine, 2022
Deni Rahmat, Clairine Devina Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, IndonesiaCorrespondence: Deni Rahmat, Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640 ...
Rahmat D, Devina C
doaj  

Engineering the Electrochemiluminescence Microenvironment: Mechanistic Roles of Nanomaterials in Aptamer‐Based Sensors

open access: yesSmall Structures, Volume 7, Issue 9, September 2026.
This review highlights how nanomaterials have transformed electrochemiluminescence (ECL) aptasensors beyond their traditional role as supports. It examines their emerging roles as new ECL luminophores and active regulators of the ECL microenvironment within aptasensors.
Ana Díaz‐Fernández   +2 more
wiley   +1 more source

KAT6A–inhibitor co‐crystal structures: tackling a challenging crystallization target via two alternative approaches

open access: yesActa Crystallographica Section D, Volume 82, Issue 9, Page 1111-1124, September 2026.
We report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Vera Puetter   +8 more
wiley   +1 more source

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