Results 111 to 120 of about 12,194 (220)

Improving the prognosis of nephropathic cystinosis

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2014
Martine TP Besouw,1,2 Elena N Levtchenko1,21Department of Pediatric Nephrology, University Hospitals Leuven, Belgium; 2Laboratory of Pediatrics, Catholic University Leuven, Leuven, BelgiumAbstract: Cystinosis is an autosomal recessive inherited lysosomal
Besouw MTP, Levtchenko EN
doaj  

Radioprotective Efficacy of Cysteamine [PDF]

open access: yesActa Radiologica: Therapy, Physics, Biology, 1964
A, BOSE, S, BOSE, P, DE
openaire   +2 more sources

Cysteamine 에 의한 세포사멸, ER 스트레스, 그리고 염증반응의 조절 기전

open access: yes, 2021
학위논문 (박사) -- 서울대학교 대학원 : 의과대학 의과학과, 2021. 2. 김인규.시스티아민은 Coenzyme A 분해과정에서 생성되는 thiolamine으로 세포내에서 PKC1, Transglutaminase 2 (TG2), caspase 3의 효소활성을 억제한다.
이진행
core  

Cysteamine selectively enhances neuropeptide Y2 receptor binding activity

open access: yes, 1992
Affinity labeling of [125I]NPY to the bovine hippocampal NPY receptor has revealed a 50 kDa specific binding protein, the Y2 receptor. Cysteamine (10 μM – 10 mM) specifically enhanced NPY specific labeling of the Y2 receptor without affecting ...
Li, Wei, Hexum, Terry D
core   +1 more source

Mitigative role of cysteamine against unilateral renal reperfusion injury in Wistar rats

open access: yesFrontiers in Pharmacology
BackgroundIschemia-reperfusion injury (IRI) is unavoidable during kidney transplant and it is responsible for delayed or non-function after kidney transplantation. Cysteamine is the standard drug in the management of nephropathic cystinosis and its extra-
Babatunde Adebola Alabi   +7 more
doaj   +1 more source

Therapeutic strategies in cystinosis: A focus on cysteamine and beyond

open access: yesExperimental and Molecular Pathology
Cystinosis is a autosomal recessive lysosomal storage disorder caused by mutations in the CTNS gene, which encodes cystinosin, a cystine transporter.
Angelo Santoro   +2 more
doaj   +1 more source

Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review

open access: yes, 2018
Achini K Makuloluwa, Fatemeh Shams Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK Abstract: Cystinosis is a rare, autosomal recessive disorder leading to defective transport of cystine out of lysosomes.
Makuloluwa AK, Shams F
core  

Cysteamine-induced duodenal ulcer and acid secretion in the rat

open access: yes, 1980
Duodenal ulcers can be produced in rats within 24 h by a single subcutaneous administration of cysteamine. To determine the role of gastric acid secretion in the pathogenesis of these ulcers, secretory and pathoanatomic studies were performed in chronic ...
Poulsen, Steen Seier
core   +1 more source

Clinical Efficacy of Cysteamine Application for Melasma: A Meta-Analysis

open access: yes
Background: Melasma is a challenging, acquired hyperpigmentary disorder. The gold standard treatment is Kligman’s formulation, which contains hydroquinone, tretinoin, and dexamethasone, but its long-term use is limited by the risk of exogenous ...
Tzong-Yuan Juang   +5 more
core   +1 more source

Effects of Cysteamine, Putrescine and Cysteamine-Putrescine Combination on 3-Methylcholanthrene-Induced Fibrosarcoma in Mice

open access: yes, 2014
Bu çalışmada farelerde 3-metilkolantren (3-MC) ile indüklenen fibrosarkoma üzerine sisteamin, putresin ve sisteamin-putresin kombinasyonunun etkileri araştırıldı. Araştırmada Mus musculus albino ırkı, 2-3 aylık ve 202.0 g ağırlığında olan toplam 135 adet
Doğan, Abdullah   +4 more
core   +1 more source

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