Results 41 to 50 of about 48,487 (203)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Effectiveness of postoperative radiotherapy after radical cystectomy for locally advanced bladder cancer [PDF]

open access: yes, 2019
BACKGROUND: Local-regional failure (LF) for locally advanced bladder cancer (LABC) after radical cystectomy (RC) is common even with chemotherapy and is associated with high morbidity/mortality.
Andriole, Gerald L   +15 more
core   +2 more sources

BcCluster: a bladder cancer database at the molecular level [PDF]

open access: yes, 2016
Background: Bladder Cancer (BC) has two clearly distinct phenotypes. Non-muscle invasive BC has good prognosis and is treated with tumor resection and intravesical therapy whereas muscle invasive BC has poor prognosis and requires usually systemic ...
Bhat, Akshay   +5 more
core   +3 more sources

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

open access: yesAdvanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu   +16 more
wiley   +1 more source

Workup and conservative management of ileal conduit-vaginal fistulas: review of literature. [PDF]

open access: yes, 2020
Ileal conduit-vaginal fistulas are a rare but challenging complication of urinary diversion. Here we identify risk factors and summarize the workup and conservative management strategies for this complication.
Chowdhury, Mashrin Lira   +3 more
core  

Robotic intracorporeal urinary diversion: practical review of current surgical techniques [PDF]

open access: yes, 2016
In this practical review, we discuss current surgical techniques reported in the literature to perform Intracorporeal Urinary Diversion (ICUD) after Robotic Radical Cystectomy (RARC), emphasizing criticisms of single approaches and making comparisons ...
Balbay, Mevlana D   +9 more
core   +1 more source

Intraoperative Evaluation of Bladder Perfusion Using Indocyanine Green Fluorescence Imaging During Total Pelvic Exenteration After Interruption of Blood Flow From the Internal Iliac Vessels

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Intraoperative ICG fluorescence imaging demonstrated that bladder perfusion was maintained through blood flow from the pubic side, even after complete division of the internal iliac vessels during total pelvic exenteration. ABSTRACT Background In lateral lymph node dissection (LLND) for locally advanced or recurrent rectal cancer, concomitant resection
Mamoru Uemura   +14 more
wiley   +1 more source

Bowel dysfunction after transposition of intestinal segments into the urinary tract : 8-year prospective cohort study [PDF]

open access: yes, 2007
Purpose Bowel function may be disturbed after intestinal segments are transposed into the urinary tract to reconstruct or replace the bladder. In 1997, our group were the first to report major bowel dysfunction in a cohort of such patients: up to 42% of ...
ABACUS Research Group   +8 more
core   +1 more source

A Robotic Urinary Bladder Enabling Volume Monitoring and Assisted Micturition

open access: yesAdvanced Intelligent Systems, EarlyView.
An implantable robotic bladder is presented that can store urine in an origami‐designed enclosure. An inductance sensing principle can monitor and transfer the urine volume in real‐time. It can actively expand based on the amount of urine collected from kidneys and apply on‐demand mechanical compression to assist urination.
Izadyar Tamadon   +4 more
wiley   +1 more source

Laparoscopic Infections in Urogenital and Gynecological System: A Systematic Review

open access: yesArchives of Clinical and Experimental Surgery, 2013
There are several advantages of laparoscopic surgery, which is employed only in the presence of some indications, as follows: minimally invasive procedure, reduced postoperative pain and analgesic use, and short hospital stay.
Hasan Ucmak   +2 more
doaj   +1 more source

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