Results 51 to 60 of about 99,648 (351)

Artificial Intelligence‐Assisted Urine Cytology for Noninvasive Detection of Muscle‐Invasive Urothelial Carcinoma: A Multi‐Center Diagnostic Study with Prospective Validation

Advanced Science, EarlyView.
Accurate preoperative detection of muscle‐invasive urothelial carcinoma (MIUC) is crucial for clinical decision‐making. This study developed PUCAS‐M, an artificial intelligence (AI) model that analyzes urine cytology to assist in differentiating MIUC from non‐MIUC.
Runnan Shen, Fan Jiang, Xiaowei Huang, Guibin Hong, Yun Luo, Huan Wan, Ye Xie, Mengyi Zhu, Yun Wang, Bohao Liu, Ping Qin, Yahui Wang, Haoxuan Wang, Hongkun Yang, Zhen Lin, Rui Chen, Nengtai Ouyang, Jian Huang, Tianxin Lin, Shaoxu Wu   +19 more
wiley   +1 more source

Robotic Cystectomy Versus Open Cystectomy: Are We There Yet?

European Urology Supplements, 2010
Introduction: Open radical cystectomy (ORC) with extended pelvic lymph node dissection (PLND) represents the treatment of choice for muscle-invasive and/or high-risk non-muscle-invasive bladder cancer (BCa), especially when it does not respond to bacillus Calmette-Guerin. However, robotic cystectomy is steadily increasing as a minimally invasive option
Jose Maria Gaya, Alberto Breda, Humberto Villavicencio, Joan Palou Redorta, Lluís Gausa, Oscar Rodríguez   +5 more
openaire   +3 more sources

Machine learning models for predicting post-cystectomy recurrence and survival in bladder cancer patients

PLoS ONE, 2019
Currently in patients with bladder cancer, various clinical evaluations (imaging, operative findings at transurethral resection and radical cystectomy, pathology) are collectively used to determine disease status and prognosis, and recommend neoadjuvant,
Zaki Hasnain, J. Mason, K. Gill, G. Miranda, I. Gill, P. Kuhn, P. Newton   +6 more
semanticscholar   +1 more source

Considerations on the Psychological Status of the Patients Undergoing Radical Cystectomy [PDF]

, 2015
The psychological impact on patients suffering radical cystectomy is twofold - (both that of the underlying neoplastic disease and that measured by the quality of life subsequent to surgery) and increases as the urinary derivation technique is less ...
Badescu, Daniel Liviu, Balalau, Cristian, Balalau, Oana Denisa, Dumitrache, Mihai, Popescu, Bogdan, Rascu, Stefan, Scaunasu, Răzvan Valentin   +6 more
core   +3 more sources

Neutrophil-to-lymphocyte ratio as a bladder cancer biomarker: assessing prognostic and predictive value in SWOG 8710 [PDF]

, 2017
No abstract ...
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration, Asano, Ferro, Gondo, Grenader, Guthrie, Krane, Linton, Lorente, Mitchell, Ojerholm, Templeton, Viers   +12 more
core   +1 more source

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Cancer Communications, EarlyView.
Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding   +20 more
wiley   +1 more source

Downstaging and Survival Outcomes Associated With Neoadjuvant Chemotherapy Regimens Among Patients Treated With Cystectomy for Muscle-Invasive Bladder Cancer

JAMA Oncology, 2018
Importance Neoadjuvant chemotherapy (NAC) followed by radical cystectomy improves survival compared with cystectomy alone for patients with bladder cancer. Although gemcitabine with cisplatin has become a standard NAC regimen, a dose-dense combination of
Charles C. Peyton, Dominic H. Tang, R. Reich, M. Azizi, J. Chipollini, J. Pow-Sang, B. Manley, P. Spiess, M. Poch, W. Sexton, M. Fishman, Jingsong Zhang, S. Gilbert   +12 more
semanticscholar   +1 more source

A systematic review of exercise and psychosocial rehabilitation interventions to improve health-related outcomes in patients with bladder cancer undergoing radical cystectomy

, 2017
Objective: Summarizing the evidence on the effects of pre- and postoperative exercise and psychosocial rehabilitation interventions on patient-reported outcomes (PROs) and physical fitness in bladder cancer patients undergoing radical cystectomy.
Bultijnck, Renée, Decaestecker, Karel, Deforche, Benedicte, Fonteyne, Valerie, Ost, Piet, Pauwels, Nele, Pieters, Ronny, Rammant, Elke, Sundahl, Nora   +8 more
core   +1 more source

Urinary diversion and bladder reconstruction/replacement using intestinal segments for intractable incontinence or following cystectomy [PDF]

, 2012
Background Surgery performed to improve or replace the function of the diseased urinary bladder has been carried out for over a century. Main reasons for improving or replacing the function of the urinary bladder are bladder cancer, neurogenic bladder ...
Cody, June D., Dublin, Norman, McClinton, Samuel, Nabi, Ghulam, Neal, David E., Pickard, Robert, Yong, Sze M.   +6 more
core   +2 more sources

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for Bacillus Calmette–Guérin Delivery of Anticancer Agents

ChemBioChem, EarlyView.
Bacillus Calmette–Guérin (BCG) immunotherapy is the gold standard for nonmuscle invasive bladder cancer (NMIBC). However, it is limited by adverse effects and resistance, despite eliciting a robust immune response. This proof‐of‐concept study explores Antigen 85‐mediated, metabolically with trehalose‐PEG4 mertansine‐labeled BCG as a novel treatment ...
Michael Grimmeisen, Xuan Wang, Melissa Weldle, Kerstin Sartory, Sara Benkhelifa, Yu Zhang, Trinh Dao, Jonas Meyer, Oliver Gorka, Olaf Groß, Claudia Jessen‐Trefzer   +10 more
wiley   +1 more source