Results 51 to 60 of about 854,876 (123)

Interpretable Graph Convolutional Neural Networks for Inference on Noisy Knowledge Graphs [PDF]

arXiv, 2018
In this work, we provide a new formulation for Graph Convolutional Neural Networks (GCNNs) for link prediction on graph data that addresses common challenges for biomedical knowledge graphs (KGs). We introduce a regularized attention mechanism to GCNNs that not only improves performance on clean datasets, but also favorably accommodates noise in KGs, a
arxiv  

Airway acidification initiates host defense abnormalities in cystic fibrosis mice

Science, 2016
Airway infections put to an acid test Most people with cystic fibrosis suffer from chronic respiratory infections. The mechanistic link between this symptom and the genetic cause of the disease (mutations that compromise the function of the cystic ...
Viral S. Shah, D. Meyerholz, X. Tang, Leah R Reznikov, M. A. Alaiwa, S. Ernst, Philip H. Karp, C. Wohlford-Lenane, K. Heilmann, Mariah Leidinger, Patrick D. Allen, J. Zabner, P. McCray, L. Ostedgaard, D. Stoltz, C. Randak, M. Welsh   +16 more
semanticscholar   +1 more source

The future of cystic fibrosis care: a global perspective.

The Lancet Respiratory Medicine, 2020
S. Bell, M. Mall, H. Gutierrez, M. Macek, S. Madge, J. Davies, P. Burgel, E. Tullis, C. Castaños, C. Castellani, C. Byrnes, F. Cathcart, S. H. Chotirmall, R. Cosgriff, I. Eichler, I. Fajac, C. Goss, P. Dřevínek, P. Farrell, A. Gravelle, T. Havermans, N. Mayer-Hamblett, N. Kashirskaya, E. Kerem, J. Mathew, E. McKone, L. Naehrlich, S. Nasr, G. Oates, C. O’Neill, Ulrike Pypops, K. Raraigh, S. Rowe, K. Southern, S. Sivam, A. Stephenson, M. Zampoli, F. Ratjen   +37 more
semanticscholar   +1 more source

An automated pipeline for computation and analysis of functional ventilation and perfusion lung MRI with matrix pencil decomposition: TrueLung [PDF]

arXiv
Purpose: To introduce and evaluate TrueLung, an automated pipeline for computation and analysis of free-breathing and contrast-agent free pulmonary functional MRI. Material and Methods: time-resolved ultra-fast bSSFP acquisitions are transferred to TrueLung, which includes image quality checks, image registration, and computation of perfusion and ...
arxiv  

A joint model for (un)bounded longitudinal markers, competing risks, and recurrent events using patient registry data [PDF]

arXiv
Joint models for longitudinal and survival data have become a popular framework for studying the association between repeatedly measured biomarkers and clinical events. Nevertheless, addressing complex survival data structures, especially handling both recurrent and competing event times within a single model, remains a challenge. This causes important
arxiv  

Cystic Fibrosis Foundation consensus guidelines for the care of individuals with advanced cystic fibrosis lung disease.

Journal of Cystic Fibrosis, 2020
S. Kapnadak, E. DiMango, D. Hadjiliadis, S. Hempstead, E. Tallarico, J. Pilewski, A. Faro, J. Albright, C. Benden, S. Blair, E. Dellon, Daniel U Gochenour, P. Michelson, B. Moshiree, I. Neuringer, Carl Riedy, T. Schindler, L. Singer, Dave Young, Lauren Vignola, Joan Zukosky, R. Simon   +21 more
semanticscholar   +1 more source

Are adult cystic fibrosis patients satisfied with medication treatment? [PDF]

Orphanet J Rare Dis
Akman ED, Yalçın N, Karcıoğlu O, Damadoğlu E, Kalyoncu AF, Demirkan K.   +5 more
europepmc   +1 more source

Cystic Fibrosis Newborn Screening: A Systematic Review-Driven Consensus Guideline from the United States Cystic Fibrosis Foundation. [PDF]

Int J Neonatal Screen
McGarry ME, Raraigh KS, Farrell P, Shropshire F, Padding K, White C, Dorley MC, Hicks S, Ren CL, Tullis K, Freedenberg D, Wafford QE, Hempstead SE, Taylor MA, Faro A, Sontag MK, McColley SA.   +16 more
europepmc   +1 more source

Exploration of Olfaction and ChiPSO in Pediatric Cystic Fibrosis. [PDF]

J Clin Med
Saak TM, Tervo JP, Moore BM, Wang AS, DiMango E, Sadeghi H, Gudis DA, Overdevest JB.   +7 more
europepmc   +1 more source

Is There a Role for Lumacaftor/Ivacaftor in Young Children with Cystic Fibrosis? [PDF]

Ann Am Thorac Soc
Martin I, Grasemann H.
europepmc   +1 more source