Results 61 to 70 of about 1,046,440 (397)
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance The inherent inaccessibility of sweat in sedentary individuals in large volume (≥10 µL) for on-demand and in situ analysis has limited our ability to capitalize on this noninvasive and rich source of information.
S. Emaminejad +13 more
semanticscholar +1 more source
Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors
European Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023 Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley +1 more source
Clinical complications in children with false-negative results in cystic fibrosis newborn screening
Jornal de Pediatria, 2022 Objective: To present signs and symptoms and clinical course in cystic fibrosis patients with false-negative newborn screening (CF NBS). Materials and methods: All children presented in this paper were covered by CF NBS.
Katarzyna Zybert +5 more
doaj
International Journal of Neonatal Screening, 2022 Pancreatitis-Associated Protein (PAP)-based Cystic Fibrosis (CF) newborn bloodspot screening (NBS) protocols detect less CFTR-Related Metabolic Syndrome (CRMS)/CF Screen Positive, Inconclusive Diagnosis (CFSPID).
Chiara Bianchimani +11 more
doaj +1 more source
Specialized pro-resolving mediator Resolvin E1 corrects the altered cystic fibrosis nasal epithelium cilia beating dynamics [PDF]
arXiv, 2023 In cystic fibrosis (CF), impaired mucociliary clearance leads to chronic infection and inflammation. However, cilia beating features in a CF altered environment, consisting of dehydrated airway surface liquid layer and abnormal mucus, has not been fully characterized.
arxiv
Science Translational Medicine, 2019 Increased airway mucus, occurs before infection or structural lung disease in early cystic fibrosis and promotes inflammation. Early changes in cystic fibrosis Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR gene.
C. Esther +22 more
semanticscholar +1 more source
Interfacial Yield Stress Response in Synthetic Mucin Solutions
Advanced Materials Interfaces, EarlyView.The solution rheology of novel synthetic mucins mimicking natural mucin domains is studied. Like many natural mucin solutions, apparent solid‐like rheology is seen. However, no bulk structural features are found to explain it. Interfacial rheology and robust modelling reveal that this arises from molecular associations at the air–water interface ...
Sumit Sunil Kumar +7 more
wiley +1 more source
Long term respiratory morbidity in patients with vascular rings: a review
Italian Journal of Pediatrics, 2023 Abnormalities in position and/or branching of the aortic arch can lead to vascular rings that may cause narrowing of the tracheal lumen due to external compression, or constriction of the oesophagus, causing symptoms that vary in relation to the ...
Federica Porcaro +6 more
doaj +1 more source
Cystic Fibrosis Lung Disease: An Overview
Respiratory care, 2019 Although better insights into the natural course of cystic fibrosis (CF) have led to treatment approaches that have improved pulmonary health and increased the life expectancy of individuals with this disorder, lung disease remains the main cause of ...
N. Turcios
semanticscholar +1 more source
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Advanced Therapeutics, EarlyView.Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe +4 more
wiley +1 more source