Results 81 to 90 of about 925,943 (256)
European Clinical Respiratory JournalTherapeutic drug monitoring (TDM) of elexacaftor/tezacaftor/ivacaftor (ETI) remains challenging due to a lack of clarity around the parameters that govern ETI plasma concentrations, whilst the use of concomitant CYP3A inducers rifabutin and rifampicin is
Claire Y Mou +10 more
doaj +1 more source
Worldwide rates of diagnosis and effective treatment for cystic fibrosis.
Journal of Cystic Fibrosis, 2022 Jonathan Guo, A. Garratt, A. Hill
semanticscholar +1 more source
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.
New England Journal of Medicine, 2011 BACKGROUND Increasing the activity of defective cystic fibrosis transmembrane conductance regulator (CFTR) protein is a potential treatment for cystic fibrosis.
N. England +19 more
semanticscholar +1 more source
Italian Journal of PediatricsBackground During the pandemic, the pneumology team at Bambino Gesù Children’s Hospital highlighted that telemedicine was a valuable tool for remotely managing the medical needs of children with medical complexity (CMC).
Alessandro Onofri +5 more
doaj +1 more source
Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor
Nature Communications, 2017 Asthma is characterized by abnormal airway hyperresponsiveness. Here the authors identify BPIFA1 as a factor secreted by airway epithelial cells, and show that it regulates contractility of airway smooth muscle cells by binding to and regulating the ...
Tongde Wu +10 more
doaj +1 more source
Improving the Rate of Sufficient Sweat Collected in Infants Referred for Sweat Testing in Michigan
Global Pediatric Health, 2014 Objective . Sweat collected for testing should have quantity not sufficient (QNS) rate of ≤10% in babies ≤3 months of age. Michigan (MI) cystic fibrosis (CF) centers’ QNS rates were 12% to 25% in 2009. This project was initiated to reduce sweat QNS rates
Ibrahim Abdulhamid MD +6 more
doaj +1 more source
Case Reports in Infectious Diseases, 2015 Introduction. P. aeruginosa is the primary cause for pulmonary destruction and premature death in cystic fibrosis (CF). Therefore, prevention of airway colonization with the pathogen, ubiquitously present in water, is essential.
Jochen G. Mainz +8 more
doaj +1 more source
Respiratory Medicine Case Reports, 2015 Cystic fibrosis (CF) is a common autosomal recessive disorder in Caucasian populations with respiratory, gastrointestinal and endocrine manifestations.
W.A.K. Al-Azzani +7 more
doaj +1 more source
Ion mediated cross-shield driven mucous swelling kinetics [PDF]
arXiv, 2013 We present an experimentally guided, bi-phasic, multi-species ionic gel model to compare and make quantitative predictions on the viscoelastic properties of healthy mucus versus Cystic-Fibrosis infected mucus. The mixture theory consists of the mucus (polymer phase) and water (solvent phase) as well as several different ions: H$^+$, Na$^+$, Cl$^-$ and ...
arxiv
Molecular Biology of the Cell, 2016 More than 2000 mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) have been described that confer a range of molecular cell biological and functional phenotypes.
Gudio Veit +17 more
semanticscholar +1 more source