Results 141 to 150 of about 117,699 (379)

Human Organoids and Their Application in Tumor Models, Disease Modeling, and Tissue Engineering

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Organoid technology has revolutionized biomedical research, disease modeling, drug discovery, and regenerative medicine by providing three‐dimensional (3D) organ‐like structures that closely mimic native human tissues. Derived from pluripotent and adult stem cells, organoids replicate the structural, cellular, and functional characteristics of
Siyuan Song, Zheng Liu, Yi Wang, Bo Gong
wiley   +1 more source

Acquired cystic kidney disease and renal tumor

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2018
Immunosuppression is a well-known risk factor for malignancy. Renal transplant patients are at high risk for cancer in the native kidneys especially in the presence of acquired cystic disease. We report a case highlighting the importance of screening for
Svetha Chunduri   +2 more
doaj   +1 more source

Operative Intervention in Cystic Disease of the Kidneys [PDF]

open access: yesThe American Journal of the Medical Sciences, 1914
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openaire   +3 more sources

The Hsp90β Isoform: An Attractive Target for Drug Development

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury   +2 more
wiley   +1 more source

Fetal Urinoma Secondary to Posterior Urethral Valve and Its Association to Postnatal Renal Function: A Multicenter Retrospective Study

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim The role of prenatal urinoma in lower urinary tract obstruction (LUTO) such as posterior urethral valves (PUV) is debated. We aimed to describe the risk factors associated with fetal urinoma and the association between fetal urinoma and postnatal renal function before 2 years of age.
Flore‐Anne Martin   +10 more
wiley   +1 more source

Renal Parenchymal Area and Kidney Collagen Content [PDF]

open access: yesarXiv, 2016
The extent of renal scarring in chronic kidney disease (CKD) can only be ascertained by highly invasive, painful and sometimes risky tissue biopsy. Interestingly, CKD-related abnormalities in kidney size can often be visualized using ultrasound. Nevertheless, not only does the ellipsoid formula used today underestimate true renal size but also the ...
arxiv  

Cystic kidney diseases [PDF]

open access: yesNephrology Dialysis Transplantation, 2013
Hanno J. Bolz   +32 more
openaire   +2 more sources

Acute kidney injury on chronic kidney disease: From congestive heart failure to light chain deposition disease and cast nephropathy in multiple myeloma [PDF]

open access: yes, 2019
Acute on chronic renal failure is a common but notably broad diagnosis. We present a 64-year-old man with a history of diastolic heart failure and chronic kidney disease, admitted for an elevated creatinine.
Cheng, Steven   +3 more
core   +1 more source

Whole Genome Sequencing in Prenatal Diagnostics: The Danish Approach to Guideline Formation and Implementation Within Public Healthcare

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To describe the implementation of whole genome sequencing (WGS) in prenatal diagnostics and outline the national guideline system facilitating this. Methods Clinical guidelines for WGS in prenatal diagnostics were developed and implemented by the Danish Fetal Medicine Society.
Ida Vogel   +17 more
wiley   +1 more source

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