Results 1 to 10 of about 645,542 (342)

Network for Early Onset Cystic Kidney Diseases—A Comprehensive Multidisciplinary Approach to Hereditary Cystic Kidney Diseases in Childhood

Frontiers in Pediatrics, 2018
Hereditary cystic kidney diseases comprise a complex group of genetic disorders representing one of the most common causes of end-stage renal failure in childhood.
Jens Christian König, Andrea Titieni, Martin Konrad, The NEOCYST Consortium, C. Bergmann, M. Cetiner, J. Drube, C. Gimpel, J. Göbel, D. Haffner, T. Illig, N. Klopp, J. König, M. Konrad, M. Lablans, M. C. Liebau, S. Lienkamp, C. Okorn, H. Omran, L. Pape, P. Pennekamp, F. Schaefer, B. Schermer, H. Storf, A. Titieni, F. Ückert, S. Weber, W. Ziegler   +27 more
doaj   +2 more sources

Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management

The Iraqi Journal of Medical Sciences, 2020
Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal ...
Saleh Akares, Ahmed Bahomil
doaj   +9 more sources

Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Journal of Clinical Medicine, 2022
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cystic kidney disease, with patients often having a positive family history that is characterized by a similar phenotype. However, in atypical cases, particularly those in
Akinari Sekine, S. Hidaka, T. Moriyama, Yasuto Shikida, Keiji Shimazu, E. Ishikawa, K. Uchiyama, H. Kataoka, Haruna Kawano, Mahiro Kurashige, Mai Sato, Tatsuya Suwabe, S. Nakatani, T. Otsuka, H. Kai, K. Katayama, S. Makabe, S. Manabe, W. Shimabukuro, K. Nakanishi, Saori Nishio, Fumihiko Hattanda, K. Hanaoka, K. Miura, H. Hayashi, J. Hoshino, K. Tsuchiya, T. Mochizuki, S. Horie, I. Narita, S. Muto   +30 more
semanticscholar   +1 more source

Mechanism and application of metformin in kidney diseases: An update.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes mellitus (T2DM), acting via indirect activation of 5' Adenosine monophosphate-activated Protein Kinase (AMPK).
A. Song, Chun Zhang, Xianfang Meng
semanticscholar   +1 more source

Genetic and Sporadic Renal Cystic Diseases During the Perinatal and Neonatal Period: Core Curriculum 2021.

American Journal of Kidney Diseases, 2021
Renal cystic disease encompasses a large variety of illnesses with variable phenotypic expression that can manifest in utero, in infancy, and in childhood. These diseases may be unilateral or bilateral and present with single or multiple cysts.
R. Raina, R. Chakraborty, S. Sethi, Deepak Kumar, K. Gibson, C. Bergmann   +5 more
semanticscholar   +1 more source

Cleavage of periostin by MMP9 protects mice from kidney cystic disease.

PLoS ONE, 2023
The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays important roles in organogenesis and disease. It exerts both protective and deleterious effects in renal pathology, depending upon its specific substrates.
Nabila Djaziri, Cindy Burel, Lilia Abbad, Zeineb Bakey, Rémi Piedagnel, Brigitte Lelongt   +5 more
doaj   +1 more source

Spectrum of Mutations in Pediatric Non-glomerular Chronic Kidney Disease Stages 2–5

Frontiers in Genetics, 2021
Renal hypodysplasia and cystic kidney diseases, the common non-glomerular causes of pediatric chronic kidney disease (CKD), are usually diagnosed by their clinical and imaging characteristics.
Xiaoyuan Wang, Huijie Xiao, Yong Yao, Ke Xu, Xiaoyu Liu, Baige Su, Hongwen Zhang, Na Guan, Xuhui Zhong, Yanqin Zhang, Jie Ding, Fang Wang   +11 more
doaj   +1 more source

An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]

, 2016
Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts.
Goldberg, Itzhak D., Narayan, Prakash, Nieto, Jake A., Yamin, Michael A.   +3 more
core   +5 more sources

Results of targeted next-generation sequencing in children with cystic kidney diseases often change the clinical diagnosis.

PLoS ONE, 2020
Cystic kidney diseases are a very heterogeneous group of chronic kidney diseases. The diagnosis is usually based on clinical and ultrasound characteristics and the final diagnosis is often difficult to be made.
Lena Obeidova, Tomas Seeman, Filip Fencl, Kveta Blahova, Jan Hojny, Veronika Elisakova, Jana Reiterova, Jitka Stekrova   +7 more
doaj   +1 more source

The critical role of the Hippo signaling pathway in kidney diseases

Frontiers in Pharmacology, 2022
The Hippo signaling pathway is involved in cell growth, proliferation, and apoptosis, and it plays a key role in regulating organ size, tissue regeneration, and tumor development.
Yuting Sun, De Jin, Ziwei Zhang, Di Jin, JiaoJiao Xue, LiYun Duan, YuQing Zhang, XiaoMin Kang, FengMei Lian, FengMei Lian   +9 more
doaj   +1 more source