Results 1 to 10 of about 617,774 (332)
Frontiers in Pediatrics, 2018 Hereditary cystic kidney diseases comprise a complex group of genetic disorders representing one of the most common causes of end-stage renal failure in childhood.
Jens Christian König +27 more
doaj +4 more sources
Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD) [PDF]
Journal of Clinical Medicine, 2022 Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cystic kidney disease, with patients often having a positive family history that is characterized by a similar phenotype. However, in atypical cases, particularly those in
Akinari Sekine +2 more
exaly +3 more sources
Cleavage of periostin by MMP9 protects mice from kidney cystic disease.
PLoS ONE, 2023 The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays important roles in organogenesis and disease. It exerts both protective and deleterious effects in renal pathology, depending upon its specific substrates.
Nabila Djaziri +5 more
doaj +2 more sources
Kidney International, 2016 Enlargement of kidney tubules is a common feature of multiple cystic kidney diseases in humans and mice. However, while some of these pathologies are characterized by cyst expansion and organ enlargement, in others, progressive interstitial fibrosis and ...
Dongmei Lu, Binghua Li, Jili Zhu
exaly +2 more sources
Cystic Kidney Disease: A Primer
Advances in Chronic Kidney Disease, 2015 Renal cystic diseases encompass a broad group of disorders with variable phenotypic expression. Cystic disorders can present during infancy, childhood, or adulthood. Often, but not always, they can be distinguished by the clinical features including age at presentation, renal imaging characteristics, including cyst distribution, and the presence ...
Monica T. Cramer, Lisa M. Guay-Woodford
openaire +3 more sources
Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management
The Iraqi Journal of Medical Sciences, 2020 Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal ...
Saleh Akares, Ahmed Bahomil
doaj +9 more sources
Cystic and inherited kidney diseases
American Journal of Kidney Diseases, 2003 Dana, Rizk, Arlene B, Chapman
openaire +3 more sources
Mechanism and application of metformin in kidney diseases: An update.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021 Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes mellitus (T2DM), acting via indirect activation of 5' Adenosine monophosphate-activated Protein Kinase (AMPK).
A. Song, Chun Zhang, Xianfang Meng
semanticscholar +1 more source
American Journal of Kidney Diseases, 2021 Renal cystic disease encompasses a large variety of illnesses with variable phenotypic expression that can manifest in utero, in infancy, and in childhood. These diseases may be unilateral or bilateral and present with single or multiple cysts.
R. Raina +5 more
semanticscholar +1 more source
Spectrum of Mutations in Pediatric Non-glomerular Chronic Kidney Disease Stages 2–5
Frontiers in Genetics, 2021 Renal hypodysplasia and cystic kidney diseases, the common non-glomerular causes of pediatric chronic kidney disease (CKD), are usually diagnosed by their clinical and imaging characteristics.
Xiaoyuan Wang +11 more
doaj +1 more source