Results 1 to 10 of about 71,622 (158)

Ciliary Genes in Renal Cystic Diseases [PDF]

Cells, 2020
Cilia are microtubule-based organelles, protruding from the apical cell surface and anchoring to the cytoskeleton. Primary (nonmotile) cilia of the kidney act as mechanosensors of nephron cells, responding to fluid movements by triggering signal ...
Anna Adamiok-Ostrowska, Agnieszka Piekiełko-Witkowska   +1 more
doaj   +2 more sources

A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adulthood ...
Sarah Myram, Bastien Venzac, Brice Lapin, Aude Battistella, Fanny Cayrac, Bertrand Cinquin, Charles Cavaniol, Charles Cavaniol, Giacomo Gropplero, Isabelle Bonnet, Sophie Demolombe, Stéphanie Descroix, Sylvie Coscoy   +12 more
doaj   +2 more sources

Localized renal cystic disease

Indian Journal of Urology, 2015
Localized renal cystic disease (LRCD) is a rare benign non-hereditary, non-progressive condition which must be differentiated from other renal cystic diseases.
Ramakrishna Narayanan, Balasubramanyam Shankar, Chaitanya D Kulkarni   +2 more
doaj   +3 more sources

Modeling Complex Developmental Disease: The Case of Polycystic Kidney Disease [PDF]

Journal of Developmental Biology
Both genetics and the environment affect the phenotypes of polycystic kidney diseases (PKD), such as autosomal dominant (AD) PKD, autosomal recessive (AR) PKD and nephronophthisis (NPH). Variable phenotypes, pleiotropy, divergent severity and progression,
Jay DeLoriea, Cody Casey, Lexee Shearer, Victoria Chen, Angelica Bryant, Chiara Gamberi   +5 more
doaj   +2 more sources

Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management

The Iraqi Journal of Medical Sciences, 2020
Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal cystic ...
Saleh A. Akares, Ahmed A. Bahomil
doaj   +9 more sources

Cleavage of periostin by MMP9 protects mice from kidney cystic disease.

PLoS ONE, 2023
The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays important roles in organogenesis and disease. It exerts both protective and deleterious effects in renal pathology, depending upon its specific substrates.
Nabila Djaziri, Cindy Burel, Lilia Abbad, Zeineb Bakey, Rémi Piedagnel, Brigitte Lelongt   +5 more
doaj   +1 more source

Study of Association between Fetal Central Nervous System Congenital Anomalies and Renal Congenital Fetal Anomalies [PDF]

Minia Journal of Medical Research, 2023
Background; Congenital fetal anomalies include postnatal metabolic abnormalities as well as morphological or functional deviations from normal. Aim and objectives; to research the relationship between renal and central nervous system congenital ...
Ahmed Ahmed, Mohamed Tawfik, Mohamed El-Swefy, Hazem Garhy   +3 more
doaj   +1 more source

Spectrum of Mutations in Pediatric Non-glomerular Chronic Kidney Disease Stages 2–5

Frontiers in Genetics, 2021
Renal hypodysplasia and cystic kidney diseases, the common non-glomerular causes of pediatric chronic kidney disease (CKD), are usually diagnosed by their clinical and imaging characteristics.
Xiaoyuan Wang, Huijie Xiao, Yong Yao, Ke Xu, Xiaoyu Liu, Baige Su, Hongwen Zhang, Na Guan, Xuhui Zhong, Yanqin Zhang, Jie Ding, Fang Wang   +11 more
doaj   +1 more source

Tuberous sclerosis complex as a rare cause of multiple nodular and cystic lung disease:a case report [PDF]

Jichu yixue yu linchuang, 2022
Objective To broaden the differential diagnosis thinking of diffuse cystic lung diseases and multiple nodular lung disease, and to deepen the understanding of clinical phenotypes of tuberous sclerosis complex (TSC).
WANG Ping, XU Zuo-jun, XU Kai-feng
doaj   +1 more source

Lipids and renal cystic disease [PDF]

Nephrology Dialysis Transplantation, 2010
Summary of key findings Glucosylceramide (GlcCer) levels were found to be higherin kidney tissue of autosomal dominant PKD/conditionalknockout mice and nephronophthisis mice (jck and pcymice) than in normal kidney tissue. The same was foundin renal tissue of human polycystic kidney disease (PKD)as compared with normal kidney tissue.
Robert W, Schrier, Moshe, Levi
openaire   +2 more sources