Results 31 to 40 of about 617,774 (332)

Wall Tension and Tubular Resistance in Kidney Cystic Conditions

Biomedicines, 2023
The progressive formation of single or multiple cysts accompanies several renal diseases. Specifically, (i) genetic forms, such as adult dominant polycystic kidney disease (ADPKD), and (ii) acquired cystic kidney disease (ACKD) are probably the most ...
Michele Della Corte, Davide Viggiano
doaj   +1 more source

Localized renal cystic disease

Indian Journal of Urology, 2015
Localized renal cystic disease (LRCD) is a rare benign non-hereditary, non-progressive condition which must be differentiated from other renal cystic diseases.
Ramakrishna Narayanan, Balasubramanyam Shankar, Chaitanya D Kulkarni   +2 more
doaj   +1 more source

Hepatocyte Nuclear Factor 1 Beta Mutation-associated Newborn Onset of Glomerulocystic Kidney Disease: A Case Presentation

Medeniyet Medical Journal, 2021
Mutations in hepatocyte nuclear factor-1 beta (HNF1B) are the most commonly identified genetic cause of renal malformations. Heterozygous mutations are associated with renal cysts and diabetes syndrome.
Nilüfer Göknar, Melda Ekici Avcı, Diana Üçkardeş, Emre Keleşoğlu, Kübra Tekkuş Ermiş, Cengiz Candan   +5 more
doaj   +1 more source

The diagnostic value of ultrasound in cystic kidney diseases

Pediatric nephrology (Berlin, West), 2010
Renal cysts in childhood can be found in a variety of diseases, which can be congenital or acquired, or renal cysts may be part of a multiorgan disease or restricted to the kidneys only.
U. Vester, B. Kranz, P. Hoyer
semanticscholar   +1 more source

Cystic Renal Disease in Children: A Broad Spectrum from Simple Cyst to End Stage Renal Failure

Turkish Journal of Nephrology, 2019
Objective: Renal cystic diseases consist of a broad spectrum of hereditary or acquired conditions that may lead to end stage renal disease. We aimed to evaluate our patients diagnosed as renal cystic disease in terms of their diagnosis, demographic ...
Neslihan Çiçek, Nurdan Yıldız, Tuğba Nur Daşar, Harika Alpay, İbrahim Gökce   +4 more
doaj   +1 more source

Clinical utility of genetic testing in Indian children with kidney diseases

BMC Nephrology, 2023
Background Kidney diseases with genetic etiology in children present with an overlapping spectrum of manifestations. We aimed to analyze the clinical utility of genetic testing in the diagnosis and management of suspected genetic kidney diseases in ...
Anshuman Saha, Shahenaz F. Kapadia, Kinnari B Vala, Himanshu V. Patel   +3 more
doaj   +1 more source

A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8

, 2012
Background Nephronophthisis (NPHP) as a cause of cystic kidney disease is the most common genetic cause of progressive renal failure in children and young adults.
Morahan, G., Mathew I Bellgard, Roberto A Barrero, Morahan, G, McCooke, J.K., Bellgard, MI, Jacqueline K Phillips, Ding, A., John K McCooke, Appels, R, Grant Morahan, Phillips, J.K., Justyna E Ozimek-Kulik, Phillips, JK, Bellgard, M.I., Barrero, RA, McCooke, JK, Appels, R., Barrero, R.A., Ozimek-Kulik, J.E., Rudi Appels, Alice Ding, Ozimek-Kulik, JE, Ding, A   +23 more
core   +1 more source

Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila. [PDF]

PLoS Genetics, 2017
Progressive cystic kidney degeneration underlies diverse renal diseases, including the most common cause of kidney failure, autosomal dominant Polycystic Kidney Disease (PKD).
Chiara Gamberi, David R Hipfner, Marie Trudel, William D Lubell   +3 more
doaj   +1 more source

Refining Kidney Survival in 383 Genetically Characterized Patients With Nephronophthisis [PDF]

, 2022
Kidney survival; Nephronophthisis; Prognostic factorsSupervivencia renal; Nefronoptisis; Factores pronósticosSupervivència renal; Nefronoftisi; Factors pronòsticsIntroduction Nephronophthisis (NPH) comprises a group of rare disorders accounting for up ...
Gerß, Joachim, Schlingmann, Karl-Peter, Karsay, Rebeka, König, Jens Christian, Telgmann, Anna-Katharina, Dahmer-Heath, Mareike, Ariceta Iraola, Gema   +6 more
core   +1 more source

Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression

EMBO Molecular Medicine
Polycystic kidney disease (PKD) is a genetic disorder characterized by bilateral cyst formation. We showed that PKD cells and kidneys display metabolic alterations, including the Warburg effect and glutaminolysis, sustained in vitro by the enzyme ...
Sara Clerici, Christine Podrini, Davide Stefanoni, Gianfranco Distefano, Laura Cassina, Maria Elena Steidl, Laura Tronci, Tamara Canu, Marco Chiaravalli, Daniel Spies, Thomas A Bell, Ana SH Costa, Antonio Esposito, Angelo D’Alessandro, Christian Frezza, Angela Bachi, Alessandra Boletta   +16 more
doaj   +1 more source