Results 41 to 50 of about 117,699 (379)

Localized renal cystic disease

Indian Journal of Urology, 2015
Localized renal cystic disease (LRCD) is a rare benign non-hereditary, non-progressive condition which must be differentiated from other renal cystic diseases.
Ramakrishna Narayanan, Balasubramanyam Shankar, Chaitanya D Kulkarni   +2 more
doaj   +1 more source

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
core   +2 more sources

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun, Lingling Cui, Robert Terkeltaub, Ying Chen, Xinde Li, Xiaoyu Cheng, Tian Liu, Nicola Dalbeth, Changgui Li   +8 more
wiley   +1 more source

Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation [PDF]

, 2014
BACKGROUND: Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease, a cilia-associated pathology (ciliopathy).
AbouAlaiwi, Wissam A., Bacallao, Robert L., Booth, Robert L., Fruttiger, Marcus, Herbert, Britney S., Joe, Bina, Liu, Lijun, Mak, Tak W., Muntean, Brian S., Nauli, Surya M., Ratnam, Shobha, Rodriguez, Ingrid, Zhou, Jing   +12 more
core   +2 more sources

Understanding Contributors of Resilience in Youth With Childhood‐Onset Systemic Lupus Erythematosus Through a Socioecological Lens: A Mixed‐Methods Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino, Louise Boulard, Joanna Law, Asha Jeyanathan, Lawrence Ng, Sandra Williams‐Reid, Kiah Reid, Angela Cortes, Eugene Cortes, Ashley Danguecan, Deborah M. Levy, Linda T. Hiraki, Andrea M. Knight   +12 more
wiley   +1 more source

Acquired cystic kidney disease

Kidney International, 1991
A 34-year-old black sales manager was referred for evaluation of azotemia of undetermined duration. He claimed to be in good health except for "borderline" hypertension since age 25. He had no history of urinary tract signs or symptoms. A tumor of unspecified type had been removed from the left anterior chest wall 8 years previously; there had been no ...
openaire   +3 more sources

Cystic Diseases of the Kidney

, 2020
Cystic diseases of the kidney range from indolent, incidentally diagnosed simple renal cysts to severe life-threatening renal insufficiency seen in neonates and infants with autosomal recessive polycystic kidney disease (ARPKD). Multicystic dysplastic kidney (MCDK) and autosomal dominant cystic disease (ADPKD) are examples of the most common cystic ...
Rodrigo L.P. Romao, Osarumwense David Osifo, Edward Hannon, Martin Situma   +3 more
openaire   +2 more sources

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression [PDF]

, 2017
Uromodulin (UMOD) mutations are responsible for three autosomal dominant tubulo-interstitial nephropathies including medullary cystic kidney disease type 2 (MCKD2), familial juvenile hyperuricemic nephropathy and glomerulocystic kidney disease.
Attanasio, Massimo, Baasner, Anne, Beck, Bodo B., Boehm, Christoph W. A., Boehnlein, Joana M., Fischer, Andreas, Hildebrandt, Friedhelm, Hopfer, Helmut, Hoppe, Bernd, Pasch, Andreas, Polishchuk, Roman S., Rampoldi, Luca, Sayer, John A., Steffens, Sarah, Wolf, Matthias T. F., Zaucke, Frank   +15 more
core  

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Complete Spontaneous Resolution of Complex Renal Cyst: A Case Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Renal cysts are the lesion which can bother to patient, treating nephrologists and urologist. Spectrum of presentation ranges from benign to malignant, familial to sporadic.
Arun Kumar Maurya, Dilip Kumar Pal
doaj   +1 more source