Intravesical hyaluronic acid treatment for ketamine-associated cystitis: Preliminary results
Introduction: Long-term ketamine abuse may cause variable lower urinary tract symptoms (LUTS) and severe cystitis. The clinical features of ketamine-associated cystitis (KC) are very similar to bladder pain syndrome/interstitial cystitis (BPS/IC ...
En Meng +7 more
doaj +1 more source
Differential regulation of bladder pain and voiding function by sensory afferent populations revealed by selective optogenetic activation [PDF]
Bladder-innervating primary sensory neurons mediate reflex-driven bladder function under normal conditions, and contribute to debilitating bladder pain and/or overactivity in pathological states. The goal of this study was to examine the respective roles
Brian M. Davis +9 more
core +3 more sources
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Interstitial cystitis/bladder pain syndrome is a chronic pelvic pain condition with no known etiology that affects millions of women and men in the United States.
Tyler L. Overholt +3 more
doaj +1 more source
Animal Models of Hunner‐Type Interstitial Cystitis
ABSTRACT Background Animal models are crucial for mechanistic studies and therapeutic development of human diseases. At present, the etiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic disease of the urinary bladder, remains undefined.
Yoshiyuki Akiyama, Yi Luo
wiley +1 more source
Interstitiaalisen virtsarakkotulehduksen eli virtsarakon kipuoireyhtymän hoito [PDF]
Kansainvälinen urologityöryhmä on ehdottanut, että termi virtsarakon kipuoireyhtymä korvaisi aiemman interstitiaalinen kystiitti -termin laajan merkityksen.
Leppilahti, Mikael +2 more
core
Purinergic receptor mediated calcium signalling in urothelial cells [PDF]
Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M +4 more
core +3 more sources
Interstitial Cystitis/Bladder Pain Syndrome in Persian Medicine view
Bladder pain syndrome or interstitial cystitis is a disagreeable feeling of pain, pressure and discomfort in the urinary bladder, along with lower urinary tract symptoms that may last more than six weeks with no infection or any other identifiable cause.
Zahra Niktabe +4 more
doaj
Einfluss psychosozialer Faktoren auf das Krankheitsgeschehen der Interstitiellen Cystitis [PDF]
Die vorliegende Arbeit beschäftigt sich mit der Frage, inwieweit psychosoziale Belastungsfaktoren in Kindheit und Erwachsenenalter Einfluss auf Krankheitsentstehung und Verlauf der interstitiellen Cystitis (IC) haben. Als Testinstrumente fanden die MSBA (
Oemler, Madlen
core
Formación de calculos renales de oxalato cálcico en mamíferos [PDF]
Calcium oxalate (CaOx) is the main inorganic component of urolithiasis and is mainly present in the formation of kidney stones in humans. Additionally, oxalocalcic urolithiasis has become the most frequent type of kidney stones, for instance, oxalocalcic
Neira-Carrillo, Andrónico +1 more
core +2 more sources

