Results 21 to 30 of about 51,607 (296)

The Efficacy and Safety of Cytarabine on Newly Diagnosed Primary Central Nervous System Lymphoma: A Systematic Review and Meta-Analysis

Frontiers in Oncology, 2020
Background: The role of cytarabine on newly diagnosed primary central nervous system lymphoma (PCNSL) remains controversial. The present study mainly aimed to assess the efficacy and safety of cytarabine in the induction treatment of PCNSL.Methods: We ...
Xiaohong Zheng, Shoubo Yang, Feng Chen, Si Wu, Wenbin Li   +4 more
doaj   +1 more source

High dose cytarabine induced myopericarditis: When the heart debilitates but the fight against cancer must be strong

Iatreia, 2022
Knowledge about cytarabine induced cardiotoxicity is scarce. We present the clinical case of a 51-year-old patient with past medical history of Acute Myeloid Leukemia managed with high doses of cytarabine and who developed acute myopericarditis as a ...
Villa-Saldarriaga, María P, Gómez-Ramírez, Luz A, Miranda-Arboleda, Andrés F, Saavedra-González, Yesid A   +3 more
doaj   +1 more source

A conservative treatment for eosinophilic cystitis

IJU Case Reports, Volume 6, Issue 1, Page 8-12, January 2023., 2023
Introduction Eosinophilic cystitis is a rare condition which causes common symptoms and may mimic other conditions. Eosinophilic cystitis has several causes such as hypereosinophilic syndrome, inflammatory diseases, neoplasia, parasites or fungal infection, IgE‐related diseases, Drug Reaction and Eosinophilia and Systemic Symptoms (DRESS) syndrome, or ...
Franco Alchiede Simonato, Nicola Pavan, Mirko Pinelli, Gabriele Tulone, Rosa Giaimo, Anna Martorana, Alchiede Simonato   +6 more
wiley   +1 more source

Primary diffuse large B cell lymphoma of the prostate in a patient with HIV infection

IJU Case Reports, Volume 6, Issue 1, Page 30-32, January 2023., 2023
Introduction Primary prostate lymphomas are very rare; however, the incidence of malignant lymphoma is high among HIV‐infected patients. Herein, we report a case of primary diffuse large B‐cell lymphoma (DLBCL) of the prostate in an HIV‐infected patient. Case presentation A 47‐year‐old man presented with miction pain and back pain.
Takashi Ujiie, Taketo Kawai, Tomoyuki Kaneko, Tadashi Yamamoto, Yasutoshi Oshima, Mutsuo Fujikura, Nobu Akiyama, Yuko Sasajima, Haruko Tashiro, Tohru Nakagawa   +9 more
wiley   +1 more source

The histological changes induced by Cytarabine on rabbits livers (with and without vitamin E administration) [PDF]

Iraqi Journal of Veterinary Sciences, 2020
The present study was intended to determine the histological changes induced by Cytarabine drug on the structure of rabbit's livers and the protective effects of vitamin E on these histological changes.
Saif Al-Jammas, Ayad Al-Saraj
doaj   +1 more source

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.

New England Journal of Medicine, 2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic-phase chronic myeloid leukemia (CML) who have had no response to interferon alfa.
S. O’Brien, F. Guilhot, R. Larson, I. Gathmann, M. Baccarani, F. Cervantes, J. Cornelissen, T. Fischer, A. Hochhaus, T. Hughes, K. Lechner, J. L. Nielsen, P. Rousselot, J. Reiffers, G. Saglio, J. Shepherd, B. Simonsson, A. Gratwohl, J. Goldman, H. Kantarjian, K. Taylor, G. Verhoef, A. Bolton, R. Capdeville, B. Druker   +24 more
semanticscholar   +1 more source

Repurposing Cytarabine for Treating Primary Effusion Lymphoma by Targeting Kaposi’s Sarcoma-Associated Herpesvirus Latent and Lytic Replications

mBio, 2018
Oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) is etiologically linked to primary effusion lymphoma (PEL), an aggressive and nontreatable malignancy commonly found in AIDS patients.
Marion Gruffaz, Shenghua Zhou, Karthik Vasan, Teresa Rushing, Qing Liu Michael, Chu Lu, Jae U. Jung, Shou-Jiang Gao   +7 more
doaj   +1 more source

Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Pediatric acute myeloid leukemia (AML) remains a challenging disease to treat even with intensified cytarabine-based chemotherapy. Histone deacetylases (HDACs) have been reported to be promising therapeutic targets for treating AML.
Xuelian Xu, Chengzhi Xie, Holly Edwards, Hui Zhou, Steven A Buck, Yubin Ge   +5 more
doaj   +1 more source

CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia

Journal of Clinical Oncology, 2018
Purpose CPX-351 is a dual-drug liposomal encapsulation of cytarabine and daunorubicin that delivers a synergistic 5:1 drug ratio into leukemia cells to a greater extent than normal bone marrow cells.
J. Lancet, G. Uy, J. Cortes, L. Newell, Tara L. Lin, E. Ritchie, R. Stuart, S. Strickland, D. Hogge, S. Solomon, R. Stone, D. Bixby, J. Kolitz, G. Schiller, M. Wieduwilt, D. Ryan, A. Hoering, Kamalika Banerjee, M. Chiarella, A. Louie, B. Medeiros   +20 more
semanticscholar   +1 more source

Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

Journal of Clinical Oncology, 2019
PURPOSE Effective treatment options are limited for patients with acute myeloid leukemia (AML) who cannot tolerate intensive chemotherapy. An international phase Ib/II study evaluated the safety and preliminary efficacy of venetoclax, a selective B-cell ...
A. Wei, S. Strickland, Jingzhou Hou, W. Fiedler, Tara L. Lin, R. Walter, A. Enjeti, I. Tiong, M. Savona, Sangmin Lee, B. Chyla, R. Popovic, A. Salem, S. Agarwal, T. Xu, Kaffa Fakouhi, R. Humerickhouse, W. Hong, J. Hayslip, G. Roboz   +19 more
semanticscholar   +1 more source