Results 141 to 150 of about 50,654 (294)

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Self‐Assembled Nanocomplexes of Oligomerized Catechins and Deoxyribonuclease‐I for Synergistically Enhancing Diabetic Wound Healing

Aggregate, Volume 7, Issue 1, January 2026.
This study develops a self‐assembled O/DNase‐I nanocomplex that eliminates neutrophil extracellular traps (NETs) and blocks their formation, accelerates diabetic ulcers (DUs) healing in mice through the synergetic effect of DNase‐I and oligomerized epigallocatechin gallate (OEGCG).
Yue Li, Yuye Yang, Huiying Zhang, Rongshuang Xin, Xinyi Pang, Tianxin Li, Wei Liu, Xin Zhou, Zinuo Zhang, Sailong Wang, Xinwei Miao, Jie Dong, Yan Zheng, Zhigui Su, Jun Chen, Mei Dong   +15 more
wiley   +1 more source

Perfluorooctanesulfonamide-induced epiboly delay is associated with decreased ATP production within zebrafish embryos

Ecotoxicology and Environmental Safety
Per- and polyfluoroalkyl substances (PFAS) persistence within environmental media has led to ubiquitous exposure within humans and wildlife. We previously found that exposure of zebrafish embryos to perfluorooctanesulfonamide (PFOSA) from 0.75 to 6 h ...
John Hoang, Nicholas Jimenez, Keivon Faizi, Qibo Xiang, Emma Fencl, Rebecca Yates, Jay Gan, David C. Volz   +7 more
doaj   +1 more source

L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. II. Isolation and structure.

, 1992
John G. Ondeyka, Otto D. Hensens, Deborah L. Zink, Richard Ball, R. B. Lingham, Gerald F. Bills, Anne W. Dombrowski, Michael Goetz   +7 more
openalex   +2 more sources

Effect of Cytochalasin B on Human Lymphocyte Responses to Mitogens: Time and Concentration Dependence [PDF]

, 1977
Rosemary A. Hoffman, Ronald M. Ferguson, Richard L. Simmons   +2 more
openalex   +1 more source

A Hypoxia‐Responsive Near‐Infrared Phosphorescence Nanoprobe for High‐Sensitive Detection of Tumor Cells and Imaging of Colorectal Cancer In Situ

Aggregate, Volume 7, Issue 1, January 2026.
We have successfully developed a hypoxia‐responsive near‐infrared phosphorescent probe, Ir‐PEG. This nanoprobe demonstrates high sensitivity, water solubility, and deep‐tissue penetration. It remains specifically activatable even in the hypoxic intestinal environment, facilitating high‐contrast imaging of orthotopic colon cancer.
Jian Chen, Huamin Lan, Sensen Zhou, Weizhi Chen, Xu Zhen, Xiqun Jiang   +5 more
wiley   +1 more source

Novel Metabolites from the Marine-Derived Fungus Peniophora sp. SCSIO41203 Show Promising In Vitro Antitumor Activity as Methuosis Inducers in PC-3 Cells

Marine Drugs
Two new cytochalasin derivatives, peniotrinins A (1) and B (2), three new citrinin derivatives, peniotrinins C–E (4, 5, 7), and one new tetramic acid derivative, peniotrinin F (12), along with nine structurally related known compounds, were isolated from
Bin Yang, Surun Shao, Mingyi Nie, Qingqing Tie, Xiaoyan Pang, Xiuping Lin, Xuefeng Zhou, Yonghong Liu, Xueni Wang, Yunqiu Li   +9 more
doaj   +1 more source

Isolation of chlamydiae in untreated and Cytochalasin B treated McCoy cells. [PDF]

, 1978
J. J. O’Neill, B M L McLean, M.H. Hambling   +2 more
openalex   +1 more source

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 1, Page 26-40, January 2026.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Altered Inflammatory Signature in a C9ORF72 ‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, Volume 74, Issue 1, January 2026.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source