Results 41 to 50 of about 1,936 (197)

Chemical Constituents from an Endophytic Fungus Z1

Natural Product Communications, 2013
A new ergosterol, 15β-hydroxyl-(22 E ,24 R )-ergosta-3,5,8,22-tetraen-one (1), along with three known ergosterols, two known cytochalasins, and two known azapholines were isolated from Chaetomium globosum Z1.
Chun-Yan Zhang, Xiao Ji, Xuan Gui, Bao-Kang Huang   +3 more
doaj   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Cytotoxic Bromine- and Iodine-Containing Cytochalasins Produced by the Mangrove Endophytic Fungus Phomopsis sp. QYM-13 Using the OSMAC Approach

, 2022
Twelve new cytochalasins, phomopchalasins D–O (1–3, 5–12, and 14), including one brominated (2) and two iodinated cytochalasins (3 and 6), together with six known analogues (4, 13, and 15–18) were isolated from the mangrove-derived fungus Phomopsis sp ...
Wencong Yang, Guisheng Wang (5615051), Wenyi Kang, Guisheng Wang, Jie Yuan, Zhigang She, Wenyi Kang (6937823), Ge Zou (1903264), Zhigang She (536569), Yan Chen (4308), Yan Chen, Jie Yuan (208425), Wencong Yang (12087116), Ge Zou   +13 more
core   +1 more source

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

Advanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li, Li Peng, Laiya Lu, Yingying Wang, Xiaolei Chen, Feng Yin, Cuijun Deng, Yu Cheng   +7 more
wiley   +1 more source

Effect of cytochalasins on cytosolic-free calcium concentration and phosphoinositide metabolism in leukocytes

, 1987
Cytochalasins are routinely used to stimulate a variety of functions in eukaryotic cells even though their precise mode of action remains to be elucidated.
DI VIRGILIO, Francesco, Pozzan T., TREVES, Susan Nella, Vaselli GM   +3 more
core   +1 more source

Two new cytochalasins from the endophytic fungus Xylaria sp. GDGJ-77B

, 2022
Two new open-chain cytochalasins, xylarchalasins A and B (1 and 2), together with six known analogues (3-8), were isolated from the endophytic fungus Xylaria sp. GDGJ-77B from the Chinese medicinal plant Sophora tonkinensis.
Li-Li Huang (619526), Wei-Feng Xu (6904019), Rui-Yun Yang (842414), Liu-Xia Lv (13898948), Zhao-Long Xu (10731061), Ben-Chao Li (10731064), Yan Luo (255674)   +6 more
core   +1 more source

Characterization of Cytochalasins and Steroids From the Ascomycete and Their Cytotoxicity

Natural Product Communications, 2019
One new cytochalasin daldinin ( 1 ), 2 known cytochalasins 2 and 3 , along with 2 steroids 4 and 5 , were characterized from the methanol extracts of the fruiting bodies of Daldinia concentrica .
Hoang Van Trung, Ping-Chung Kuo, Nguyen Ngoc Tuan, Nguyen Thi Ngan, Nguyen Quang Trung, Nguyen Tan Thanh, Ha Viet Hai, Doan Lan Phuong, Bach Long Giang, Yue-Chiun Li, Tian-Shung Wu, Tran Dinh Thang   +11 more
doaj   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

10-Phenyl-[12]-cytochalasins Z₇, Z₈, and Z₉ from the Marine-Derived Fungus Spicaria elegans

, 2016
The three new 10-phenyl-[12]-cytochalasins Z7, Z8, and Z9 (1−3), together with two known analogues, cytochalasins E (4) and K (5), were isolated from the marine-derived fungus Spicaria elegans.
Qianqun Gu (1433620), Rui Liu (54031), Hongbing Liu (291584), Tianjiao Zhu (1433617), Yuchun Fang (2400697), Guotao Fan (2538271), Chengbin Cui (2538274), Weiming Zhu (391049)   +7 more
core   +2 more sources

Cytotoxic Cytochalasins and Other Metabolites from Xylariaceae sp. FL0390, a Fungal Endophyte of Spanish Moss

Natural Product Communications, 2015
Two new metabolites, 6-oxo-12-norcytochalasin D (1) and 4,5-di-isobutyl-2(1H)-pyrimidinone (2), together with seven known metabolites, cytochalasins D (3), Q (4), and N (5), 12-hydroxyzygosporin G (6), heptelidic acid chlorohydrin (7), (+)-heptelidic ...
Ya-ming Xu, Bharat P. Bashyal, Mangping X. Liu, Patricia Espinosa-Artiles, Jana M. U'Ren, A. Elizabeth Arnold, A. A. Leslie Gunatilaka   +6 more
doaj   +1 more source