Results 71 to 80 of about 1,936 (197)
International Journal of Cancer, EarlyView.Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn +13 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2016 Fungi of the genus Paracoccidioides are responsible for paracoccidioidomycosis. The occurrence of drug toxicity and relapse in this disease justify the development of new antifungal agents.
Graziele Mendes +8 more
doaj +1 more source
On the Assembly of Actin Polymerization‐Powered Motors
Macromolecular Rapid Communications, EarlyView.Actin polymerization‐powered motors have the highest speed when the actin recruiting‐polymerizing proteins are immobilized in polymer brushes on their surface. These motors orbit around larger tracer particles at pH above the isoelectric point of ActA but dock onto the tracer particles’ surface at lower pH. ABSTRACT Nano‐ and micromotors are a class of
Miguel A. Ramos Docampo +2 more
wiley +1 more source
, 1993 In contrast to cytochalasin D which selectively prevents differentiation of female gametangia, cytochalasins A, B and E also masculinizeAllomyces arbuscula by preventing septation between female and male gametangia, thereby allowing the dominant ...
Nguyen Thi Bich, Nga, Turian, Gilbert
core +1 more source
, 2022 Trypanocidal and leishmanicidal activities of cytochalasins A–D against intracellular T. cruzi Tulahuen LacZ and L. infantum amastigotes and cytotoxicity for fibroblasts (HFF-1), human macrophages (THP-1) and hepatocytes (HepG2).
Rafael Consolin Chelucci (10178764) +6 more
core +1 more source
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
Effects of cytochalasins on Neurospora crassa
, 1980 Growth of various strains of Neurospora crassa in the continued presence of cytochalasins A and B results in the following pattern. At low concentration the drugs cause an increase in branching which, depending on the strain, may also reveal an increase ...
Sussman, Alfred S. +2 more
core +1 more source
Translational Oncology, 2015 An effective and inexpensive protocol for producing cytochalasins A and B is being disclosed to propose a viable method by which to examine the in vivo antineoplastic activity of these congeners in preclinical tumor-bearing mammalian models. In addition,
Matthew Trendowski +4 more
doaj +1 more source
Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?
Environmental Toxicology, EarlyView.ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves +3 more
wiley +1 more source