Results 151 to 160 of about 414,611 (257)

Overview of pathways and dynamic interactions of c-type cytochromes in Geobacter sulfurreducens. [PDF]

Biochem Soc Trans
Almeida A, Silva MA, Antunes JMA, Fernandes MV, Morgado L, Salgueiro CA.   +5 more
europepmc   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Factors Influencing Phenoconversion in CYP-Mediated Drug Metabolism: A Scoping Review. [PDF]

Pharmacy (Basel)
Scodellaro S, Triantafilou S, Cohn I.
europepmc   +1 more source

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

Angewandte Chemie, EarlyView.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero, Line Mørkholt Lund, Lasse Hyldgaard Klausen, Obinna Markraphael Ajunwa, Mingdong Dong, Rikke Louise Meyer, Victoria Birkedal, Kai Thormann   +7 more
wiley   +2 more sources

Drug development targeting the mitochondrial respiratory chain of Sparganum proliferum: Initial biochemical and drug discovery insights into the enigmatic helminth parasite. [PDF]

PLoS Negl Trop Dis
Enkai S, Nakano Y, Koyanagi M, Arimura Y, Kanuka H, Ishiwata K.   +5 more
europepmc   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Lysine or histidine? examining the role of the proximal ligand at the active heme center of cytochrome c nitrite reductase. [PDF]

J Biol Inorg Chem
Hermann B, Rudolf M, Messerschmidt A, Simon J, Einsle O, Kroneck PMH.   +5 more
europepmc   +1 more source

BACTERIAL CYTOCHROMES

Bacteriological Reviews, 1954
openaire   +2 more sources

Mechanistic Insights into <i>Vernonia calvoana</i>-Induced Apoptosis in Ovarian Cancer Cells via the Intrinsic Pathway. [PDF]

Int J Mol Sci
Chitoh AM, Yedjou CG, Tchakoua IK, Njiki S, Noubissi FK, Komolafe T, Komolafe K, Odubanjo OV, Tchounwou PB.   +8 more
europepmc   +1 more source