Induction of ROS mediated genomic instability, apoptosis and G0/G1 cell cycle arrest by erbium oxide nanoparticles in human hepatic Hep-G2 cancer cells [PDF]
Scientific Reports, 2022 The remarkable physical and chemical characteristics of noble metal nanoparticles, such as high surface-to-volume ratio, broad optical properties, ease of assembly, surfactant and functional chemistry, have increased scientific interest in using erbium ...
Gehan Safwat +2 more
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Neodymium Nitrate Suppresses Malignant Phenotypes in Hep-G2 Cells by Targeting Nrf2 to Inhibit EMT and Induce Ferroptosis [PDF]
ToxicsHepatocellular carcinoma (HCC) is characterized by a poor prognosis, largely driven by metastasis and therapy resistance, processes closely linked to epithelial–mesenchymal transition (EMT) and ferroptosis.
Jing Leng +4 more
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Frankincense oil nanoemulsion induces selective cytotoxicity and over ROS-mediated oxidative stress and apoptotic DNA damage in Hep-G2 hepatic cancer cells [PDF]
Scientific ReportsFrankincense oil nanoemulsion (FONE) exhibits high bioavailability, enhanced cellular uptake, and improved kinetic stability, making it a promising candidate for therapeutic applications.
Hanan R. H. Mohamed +2 more
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Enhancement of apoptosis in Caco-2, Hep-G2, and HT29 cancer cell lines following exposure to Toxoplasma gondii peptides [PDF]
Drug Target InsightsObjective: Cancer or neoplasm is a cosmopolitan catastrophe that results in more than 20 million new cases and 10 million deaths every year. Some factors lead to carcinogenesis like infectious diseases. Parasites like Toxoplasma gondii, by its components,
Firooz Shahrivar +3 more
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Multimodal Analytical Platform Coupled With Biological Assays Unravels Tissue-Specific Chemical Profiles, Spatial Metabolite Distributions and Bioactivities of Root Xylem and Root Bark of <i>Tripterygium wilfordii</i>. [PDF]
Anal Sci AdvABSTRACT Characterising chemical and biological differences among different tissues of medicinal plants is important for understanding their tissue‐specific characteristics and medicinal efficacy. The root xylem (RX) and root bark (RB) of Tripterygium wilfordii have historically been used differently; however, the basis underlying their differential ...
Zhang ZM +5 more
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Pharmaceutics, 2022 The objective of the present study is to evaluate the cytotoxicity of Taiwania cryptomerioides essential oil and its phytochemical on the Hep G2 cell line (human hepatocellular carcinoma).
Guan-Rong Chen +4 more
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Biomedicines, 2023 Molecular hybridization has emerged as the prime and most significant approach for the development of novel anticancer chemotherapeutic agents for combating cancer.
Ameer Fawad Zahoor +11 more
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Bi-module sensing device to in situ quantitatively detect hydrogen peroxide released from migrating tumor cells. [PDF]
PLoS ONE, 2015 Cell migration is one of the key cell functions in physiological and pathological processes, especially in tumor metastasis. However, it is not feasible to monitor the important biochemical molecules produced during cell migrations in situ by ...
Ling Yu +5 more
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Toxicity study of Gloydius brevicaudus venom on Hela and Hep G2 cells [PDF]
BIO Web of Conferences, 2023 The purpose of this study was to explore the cytotoxicity of Gloydius brevicauda venom on tumor cells. Hela and Hep G2 cells were used as the research subjects.
Hu Jianguo +2 more
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Transferrin-conjugated liposomes loaded with novel dihydroquinoline derivatives as potential anticancer agents. [PDF]
PLoS ONE, 2017 A series of 1,2-dihydroquinoline derivatives were synthesized and evaluated for cytotoxicity in HeLa, Hep G2 and 6HEK-293T cell lines. EEDQ2 was identified as a promising anti-cancer agent with low IC50 in HeLa (18.55μg/ml) and Hep G2 (14.53μg/ml) cells.
Mengqiao Wang +8 more
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