Results 291 to 300 of about 833,395 (340)

Strategies to inhibit steroid cytochrome P450 enzymes to benefit human health: development of steroid ligands for P450s 17A1, 19A1, and 8B1 to treat cancer and obesity. [PDF]

RSC Med Chem
Ho TM, Yoshimoto FK.
europepmc   +1 more source

Maximal use of 0.05% topical isotretinoin in patients with congenital ichthyosis results in low systemic exposure

British Journal of Clinical Pharmacology, EarlyView.
Abstract Congenital ichthyoses (CI) are rare, inherited skin disorders characterized by hyperkeratosis, scaling and fissuring that significantly impair patients' quality of life. Treatment options are limited, with systemic retinoids reserved for severe cases owing to their adverse effect profile.
Holm Schneider, Christopher G. Bunick, Kathrin Hillmann, Thy N. Huynh, Steven Kempers, Nicolai Peschel, Ulrike Blume‐Peytavi, Joyce M. C. Teng, Alan M. Mendelsohn, John Stinson, Lara Wine Lee   +10 more
wiley   +1 more source

Mitochondrial Collapse Responsible for Chagasic and Post-Ischemic Heart Failure Is Reversed by Cell Therapy Under Different Transcriptomic Topologies. [PDF]

Curr Issues Mol Biol
Iacobas DA, Manzoor S, Daniels D, Iacobas S, Xi L.   +4 more
europepmc   +1 more source

Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates

Megan E Wolf, D.J. Hinchen, J.E. McGeehan, Lindsay D. Eltis   +3 more
openalex   +1 more source

H⁺-capacitor and ATP production in obligate alkaliphilic <i>Bacillaceae</i>: insights into cytochrome <i>c</i> and H⁺ transport mechanisms. [PDF]

Front Microbiol
Yumoto I.
europepmc   +1 more source

Multiple entanglements of different cell death pathways, in which caspase-8 and BID interact with cardiolipin*, have been identified. [PDF]

Front Cell Dev Biol
Petit PX.
europepmc   +1 more source

A mismatch in enzyme-redox partnerships underlies divergent cytochrome P450 activities between human hepatocytes and microsomes. [PDF]

Commun Biol
Bapiro TE, Martin S, Blacker TS, Wilkinson SD, Orton AL, Hariparsad N, Jones RDO, Duchen MR, Harlfinger S.   +8 more
europepmc   +1 more source

siRNA-mediated inhibition of NTT-MMP-2 reduces oxidative stress and apoptotic signaling in an ex vivo model of ischemia/reperfusion injury. [PDF]

Sci Rep
Rak-Pasikowska A, Kamińska M, Niechciała M, Ilkowska S, Krysta A, Hałucha K, Olejnik A, Krzywonos-Zawadzka A, Sawicki G, Marek G, Bil-Lula I.   +10 more
europepmc   +1 more source