Results 171 to 180 of about 358,220 (258)

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

Synthesis of Six Natural Products Enabled by Selective Hydroxylation of Orcinaldehyde‐Like Substrates With an Enzyme Library

Angewandte Chemie, EarlyView.
Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez, Evan O. Romero, Jonathan C. Perkins, Diego N. Rojas, Maximilian S. Hrigora, Alison R. H. Narayan   +5 more
wiley   +2 more sources

Mitochondrial Genome-Encoded Long Noncoding RNA <i>Cytochrome B</i> (Lnc<i>CytB</i>) and Mitochondrial Ribonucleases in Diabetic Retinopathy. [PDF]

Biomedicines
Kumar J, Malaviya P, Kowluru RA.
europepmc   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +2 more sources

Redox partner exchanges between spatially confined complexes control the coupling effect of cytochrome b₅ on P450 CYP3A4. [PDF]

Sci Rep
Urban P, Perret A, Pompon D.
europepmc   +1 more source

Cytauxzoon felis cytochrome b gene mutation associated with atovaquone and azithromycin treatment. [PDF]

J Vet Intern Med, 2020
Hartley AN, Marr HS, Birkenheuer AJ.
europepmc   +1 more source

Drastic Reduction in Cytochrome b₆/f Complex Confers Robust PSI Photoprotection Under Fluctuating Light at the Expense of Photosynthetic Capacity. [PDF]

Physiol Plant
Kono M, Kodama H, Tanigawa K, Terashima I, Yamori W.   +4 more
europepmc   +1 more source

Evolutionary-conserved RLF, a cytochrome b₅-like heme-binding protein, regulates organ development in Marchantia polymorpha. [PDF]

New Phytol
Iwata KP, Shimizu T, Sakai Y, Furuya T, Fukumura H, Kondo Y, Masuda T, Ishizaki K, Fukaki H.   +8 more
europepmc   +1 more source

A PARTIAL SEPARATION AND CHARACTERIZATION OF CYTOCHROME OXIDASE AND CYTOCHROME b

Journal of Biological Chemistry, 1950
Bertram. Eichel, W.W. Wainio, P. Person, S.J. Cooperstein   +3 more
openaire   +1 more source