Results 101 to 110 of about 42,048 (270)

Cross‐stage single‐cell and spatial metabolome analyses reveal periderm specialization and tanshinone biosynthesis in Salvia miltiorrhiza roots

New Phytologist, EarlyView.
Biosynthesis and accumulation of tanshinones in the periderm of Salvia miltiorrhiza during secondary root growth. Summary Perennial herbs develop long‐lived roots that undergo repeated cycles of secondary growth, during which the periderm functions as a protective barrier and a major site of specialized metabolite accumulation.
Licheng Liu, Lianchong Gao, Zhi‐Ying Wang, Yan Liu, Huifeng Ju, Huana Lin, Zheng Shi, Wen‐Juan Cai, Xue Li, Yan‐Bo Huang, Yu Kong, Jing‐Jing Xu, Hong‐Peng Chen, Xin Fang, Juan Guo, Yong‐Hong Hu, Ke Chen, Xiao‐Ya Chen, Jie Hao, Lei Yang   +19 more
wiley   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng, Huan Li, Jun Wang, Li‐Chao Wang, Hui‐Zi Liu, Xiao‐Feng Dai, Steven J. Klosterman, Jie‐Yin Chen, Krishna V. Subbarao, Feng‐Mao Chen, Dan‐Dan Zhang   +10 more
wiley   +1 more source

Studies On Cytochrome P-450 in Some Higher Plants.

, 2020
This thesis presents data obtained on the nature and roles of cytochrome P-450 in some higher plant tissues. The following were found, by spectral investigation, to have specific microsomal P-450 concentrations of the same order of magnitude as rat liver:
Cottrell, Suzanne.
core  

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Effect of portal arterialization on hepatic cytochrome P 450 in rats with portacaval shunt

, 1975
Fractional clearance of colloidal gold particles (k), liver weight and hepatic cytochrome P 450 were measured in rats with portacaval shunt and in rats with portacaval shunt plus arterialization of the hepatic stump of the portal vein.
Lambilliotte, Jean-Pierre, Pector, Jean Claude, Verbeustel, Suzanne   +2 more
core  

Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

, 2013
Pyrethroid insecticides are used to control diseases spread by arthropods. We have developed a suite of pyrethroid mimetic activity-based probes (PyABPs) to selectively label and identify P450s associated with pyrethroid metabolism.
O'Neill, Paul, Paine, Mark, Henderson, Colin, Hong, David W., Hong, David, Cravatt, Benjamin F., O'Neill, Paul M., Henderson, Colin J., Mahmoud, Hanafy, Finn, Robert D., Paine, Mark J. I., Finn, Robert, Ismail, Hanafy, Wright, Aaron T., Cravatt, Benjamin, Wright, Aaron, Paine, Mark; id_orcid, Hemingway, Janet, Ismail, Hanafy M.   +18 more
core   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Ontogeny of the chicken cytochrome P-450 enzyme system

Biochemical Pharmacology, 1987
Nancy A. Lorr, Stephen E. Bloom
openaire   +1 more source

Metabolic processing of 2-acetylaminofluorene by microsomes and six highly purified cytochrome P-450 forms from rabbit liver

, 1984
Kinetic analysis of oxidative metabolism of 2-acetylaminofluorene (AAF) was studied in control and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced microsomes and with six highly purified cytochrome P-450 isoenzymes from rabbit liver.
Schwartz, Dolores, Sanderson, Nancy, Mcmanus, Michael E., Thorgeirsson, Snorri S., Minchin, Rodney F., Johnson, Eric F.   +5 more
core   +1 more source