Results 201 to 210 of about 506,903 (380)

Long‐term treatment with carbamazepine restores cognitive abilities in a mouse model of KCNQ2 developmental and epileptic encephalopathy

Epilepsia Open, EarlyView.
Abstract Objective Carbamazepine is the first line treatment for patients affected by KCNQ2 developmental and epileptic encephalopathy. It is efficient to reduce or stop seizures in this context. However, its effect on the neurodevelopmental outcomes is debated.
Jordane Louis, Natalia Doudka, Marie‐Solenne Félix, Adeline Spiga Ghata, Camille Espanet, Romain Guilhaumou, Mathieu Milh, Laurent Villard   +7 more
wiley   +1 more source

A new naphthalene-based fluorogenic substrate for cytochrome P450 4A11. [PDF]

Biochem J
Davydov DR, Ponraj K, Davydova N, Singh DK, Prasad B.   +4 more
europepmc   +1 more source

A Novel Adrenocorticotropin-Inducible Cytochrome P450 from Rat Adrenal Microsomes Catalyzes Polycylic Aromatic Hydrocarbon Metabolism*

, 1991
Stephanie Otto, Craig B. Marcus, Charles Pidgeon, Colin R. Jefcoate   +3 more
openalex   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

Editorial for the Special Issue "Cytochrome P450 (CYP) in Health and Disease". [PDF]

Biomedicines
Grishanova A.
europepmc   +1 more source

A single amino acid substitution confers progesterone 6 beta-hydroxylase activity to rabbit cytochrome P450 2C3.

, 1993
Mei‐Hui Hsu, Keith J. Griffin, Yongjun Wang, B. Kemper, Eric F. Johnson   +4 more
openalex   +1 more source

Oxidative Assemblies of Flavonoids (Quercetin, Morin) to Form Dimer in Weak Base Circumstances and Its Mechanism Analysis by UPLC‐ESI‐TSQ‐MS/MS

Food Chemistry International, EarlyView.
Product identification of flavonoids under weak base conditions and mechanism analysis of dimer formation by the oxidative assembly of quercetin and morin, respectively. ABSTRACT Flavonoids are susceptible to autoxidation in aqueous solutions, which is largely dependent on pH, generating various free radicals and oxidation products. Quercetin and morin
Pengren Zou, Susan Jyakhwo, Paz Otero, Shengxiong Chen, Celia Costas, Carla Cameselle, Fan Zhang, Hui Cao   +7 more
wiley   +1 more source

A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects

Future Postharvest and Food, EarlyView.
ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao, Jingyimei Liang, Xincheng Wu, Mohamed A. Farag, Predrag Putnik   +4 more
wiley   +1 more source

Properties of "Stable" Mosquito Cytochrome P450 Enzymes. [PDF]

Insects
Tzotzos G.
europepmc   +1 more source

Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1

, 1993
Ronald M. Laethem, Michael Balazy, John R. Falck, Carmen Laethem, Dennis R. Koop   +4 more
openalex   +1 more source