Results 291 to 300 of about 308,115 (327)

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Cannabinoids and the endocannabinoid system in the regulation of cytochrome P450 metabolic activity-a review. [PDF]

Front Pharmacol
Fonseca CDF, Zendulka O, Juřica J.
europepmc   +1 more source

Functional studies on the cytochrome P450 splice variants CYP4F3A and CYP4F3B unveil the basis for their distinct physiological functions. [PDF]

Drug Metab Dispos
Alves Chagas BC, Brixius B, Pirhadi S, Mirtchev A, Ray S, Koes DR, Brixius-Anderko S.   +6 more
europepmc   +1 more source

GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes. [PDF]

Clin Pharmacol Ther
Coulter AJ, Thamilselvan M, Kennedy JL, Zai CC, Tiwari AK.   +4 more
europepmc   +1 more source

Functional Annotation and Comparative Analysis of Cytochrome P450 Protein Family Genes in Nine Chironomidae Species. [PDF]

Biology (Basel)
Liu W, Zhou A, Nie J, Shao Z, Nie Z, Zhang Y, Liu C, Yan C, Gao S, Wang Y.   +9 more
europepmc   +1 more source

Drug-drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450. [PDF]

Br J Clin Pharmacol
Purohit VS, Huh Y, Dowty ME, Plotka A, Lejeune A, Kalluru H, Hee B.   +6 more
europepmc   +1 more source

Alteration of drug pharmacokinetics with medicinal plant Viscum album L. by rendering major cytochrome P450 activities

, 2018
Alaattin Şen, Gurbet Celik‐Turgut, Amg Gencler-Ozkan, Orhan Adalı   +3 more
openalex   +1 more source

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Plant cytochrome p450

Phytochemistry, 1994
The present status of plant cytochrome P450 research is reviewed. A comparison of the properties of this group of cytochrome proteins with those of other microsomal b-type haem proteins is made. The range of reactions catalysed by P450s is discussed as well as recent progress in improving purification and reconstitution.
G P, Bolwell, K, Bozak, A, Zimmerlin
openaire   +2 more sources