Results 51 to 60 of about 26,184 (298)

Pharmacological regulation of the activity of cytochrome P450 3A4 AND P450 2C9 isoenzymes by vitamins and natural compounds

Регуляторные исследования и экспертиза лекарственных средств, 2018
The influence of vitamins with antioxidant properties (vitamins A, E, C), B vitamins (B1, B2, B6) and vitamin-like substances (coenzyme Q10, taurine and L-carnitine) on the enzymes of the first phase of xenobiotic metabolism - cytochromes P450 3A4 and ...
E. V. Shikh, A. A. Makhova, V. V. Shumyantseva, O. A. Demidova   +3 more
doaj  

Carboxylate-controlled electron transfer in Bacillus clausii J1G-0%B halophilic microbial fuel cells

Journal of Electrochemical Science and Engineering
Microbial fuel cells (MFCs) provide a cohesive approach to treating hypersaline wastewater and generating renewable energy. This research assessed the efficacy of halophilic Bacillus clausii J1G-0%B supplemented with acetate, lactate, or citrate at doses
Marcelinus Christwardana, Aprilia Budiarti, Mukhammad Asy'ari   +2 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Ligand-Protein Interactions in Cytochromes

, 2011
Cytochromes are found in all living beings and play an essential role in life processes. The two proteins studied in this thesis, cytochrome P450 carries out enzymatic reactions, metabolizes drugs, and synthesizes steroids while cytochrome c553 is a ...
Catalano, Jaclyn
core   +1 more source

In Silico Toxicological Assessment and Efficacy of Activated Carbon Derived from Low-Quality Face Tissues for Eosin Dye Adsorption

Iraqi Journal of Industrial Research
Eosin dye is an efficient qualitative and quantitative chemical through various scientific and biological uses but it was demonstrated as a lethal substance to animal or human lung, liver, eye, kidney, Central Nerve System (CNS) and parts of ...
Safauldeen Adnan, Salwan Sufyan Ibrahim, Ammar Salim Manati, Kafa Khalaf Hammud   +3 more
doaj   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

In situ determination of the reduction levels of cytochromes b and c in growing bacteria: a case study with N2-fixing Azorhizobium caulinodans

, 1993
The determination of the in situ reduction levels of cytochromes b and c in growing bacteria is achieved by coupling a chemostat with a dual wavelength spectrophotometer. Visible light absorption spectra of cytochromes present in bacterial cells actively
van Verseveld, H W, Stoof, C., Boogerd, F C; id_orcid, Boogerd, F C, Pronk, A.F., Oltmann, L F, Stouthamer, A.H.   +6 more
core   +1 more source

Brassica napus cytochrome P450 superfamily: Origin from parental species and involvement in diseases resistance, abiotic stresses tolerance, and seed quality traits

Ecotoxicology and Environmental Safety
Cytochromes P450 monooxygenases (CYP450s) constitute the largest enzymic protein family that is widely present in plants, animals, and microorganisms, participate in numerous metabolic pathways, and play diverse roles in development, metabolism, and ...
Yufei Xue, Shanshan Wang, Qiheng Zhang, Fangzhou Wu, Li Huang, Shujun Qin, Min Zhang, Xiao Yang, Zihan Deng, Huanhuan Jiang, Lejing Li, Yourong Chai   +11 more
doaj   +1 more source

Expanding the Regulon of the Bradyrhizobium diazoefficiens NnrR Transcription Factor: New Insights Into the Denitrification Pathway

Frontiers in Microbiology, 2019
Denitrification in the soybean endosymbiont Bradyrhizobium diazoefficiens is controlled by a complex regulatory network composed of two hierarchical cascades, FixLJ-FixK2-NnrR and RegSR-NifA.
Andrea Jiménez-Leiva, Juan J. Cabrera, Emilio Bueno, María J. Torres, Sergio Salazar, Eulogio J. Bedmar, María J. Delgado, Socorro Mesa   +7 more
doaj   +1 more source

Stretchable and Strain‐Tolerant Gold‐Coated Fibrous Biosensor for Superoxide Anion Monitoring

Advanced Materials Technologies, EarlyView.
A breathable, stretchable gold nanomesh–TPU fiber platform is developed via controlled electroless deposition, enabling uniform through‐thickness conductivity while preserving porosity. Functionalized with superoxide dismutase, the system achieves selective, real‐time electrochemical detection of superoxide with high sensitivity, mechanical durability,
Jafar M. Batayneh, Ahyeon Koh
wiley   +1 more source