Results 61 to 70 of about 26,184 (298)

Cytochromes P460 and c′-beta; A new family of high-spin cytochromes c

, 2007
Cytochromes-P460 of Nitrosomonas europaea and Methylococcus capsulatus (Bath), and the cytochrome c′ of M. capsulatus, believed to be involved in binding or transformation of N-oxides, are shown to represent an evolutionarily related new family of ...
Klotz, Martin G., Hooper, Alan B., Bradley O. Elmore, Bergmann, David J., Elmore, Bradley O, Klotz, Martin G, Elmore, Bradley O., Hooper, Alan B, Alan B. Hooper, Martin G. Klotz, David J. Bergmann, Bergmann, David J   +11 more
core   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

In vitro studies on cytochrome c biogenesis

, 2003
C-type cytochromes are essential for almost all organisms and are mainly involved in electron transport; they are characterised by the covalent attachment of heme to protein through two thioether bonds to a CXXCH peptide motif.
Daltrop, Oliver., Daltrop, Oliver
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Protein engineering of cytochromes P-450

, 2000
The cytochromes P-450 are an immensely important superfamily of heme-containing enzymes. They catalyze the monooxygenation of an enormous range of substrates.
Chapman, SK, Michael A Noble, Caroline S Miles, Tobias W.B Ost, Munro, Andrew, Stephen K Chapman, Miles, Caroline S, Miles, Caroline S., Andrew W Munro, Munro, Andrew W, Noble MA, Ost, Tobias W B, Noble, Michael A, Chapman, Stephen K   +13 more
core   +1 more source

Mechanistic studies of the phenobarbital-type induction of cytochromes P450 : role of AMP-activated protein kinase [PDF]

, 2007
Inside the liver cells there are sophisticated mechanisms that have evolved over millions of years to metabolize toxic substances, many of which are fat-soluble compounds making them difficult for the body to excrete.
Blättler, Sharon
core   +1 more source

Role of multiheme cytochromes involved in extracellular anaerobic respiration in bacteria [PDF]

, 2020
Heme containing proteins are involved in a broad range of cellular functions, from oxygen sensing and transport to catalyzing oxidoreductive reactions.
Catarina M. Paquete, Edwards, Marcus J, Richardson, David J, David J. Richardson, Clarke, Thomas A, Edwards, Marcus J., Richardson, David J., Paquete, Catarina M., Clarke, Thomas A., Thomas A. Clarke, Paquete, Catarina M, Marcus J. Edwards   +11 more
core   +1 more source

Co-Culturing Bacillus Strains for Enhanced Antimicrobial Activity

Antibiotics
Background/Objectives: Bacillus probiotic mixtures have been used as a novel source of antimicrobial production. However, there is a need to emphasize the potential of co-cultured Bacillus strains and to understand the underlying mechanisms involved in ...
Charlie Tran, Russell S. Addison, Ian E. Cock, Xiaojing Chen, Yunjiang Feng   +4 more
doaj   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Expression of c-type cytochromes and PilA content in Δgsu1771 and wild-type biofilms.

, 2023
A) SDS-heme staining from whole biofilm extracts. The asterisks indicate the major c-type cytochromes in the Δgsu1771 biofilm. Western blot analysis of OmcS (B), OmcZ (C), and PilA (D) in biofilms.
Luis M. Rodríguez-Torres (17283668), Juan B. Jaramillo-Rodríguez (17283665), Leticia Vega-Alvarado (258259), Katy Juarez (5868950), Alberto Hernández-Eligio (10218731), Guillermo A. Huerta-Miranda (17283671)   +5 more
core   +1 more source