Results 301 to 310 of about 22,374,088 (435)

Molecular Cytogenetic Analysis of Prostatic Adenocarcinomas from Screening Studies [PDF]

open access: bronze, 2001
Janneke C. Alers   +9 more
openalex   +1 more source

Olutasidenib demonstrates significant clinical activity in mutated IDH1 acute myeloid leukaemia arising from a prior myeloproliferative neoplasm

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1121-1128, April 2025.
Outcomes with olutasidenib appear appreciably better than previous reports of other therapies for blast‐phase myeloproliferative neoplasm (MPN), supporting the role for olutasidenib‐based therapy in mIDH1 AML secondary to MPN. Summary Acute myeloid leukaemia (AML) arising from a myeloproliferative neoplasm (MPN) is more aggressive and less responsive ...
Stéphane De Botton   +13 more
wiley   +1 more source

Cytogenetic Analysis of 570 Couples with Recurrent Pregnancy Loss: Reporting 11 Years of Experience. [PDF]

open access: yesJ Hum Reprod Sci, 2020
Alibakhshi R   +4 more
europepmc   +1 more source

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials [PDF]

open access: bronze, 2001
Panagiotis Kottaridis   +11 more
openalex   +1 more source

Prevalence of cytopenia(s) and somatic variants in patients with DDX41 mutant germline predisposition syndrome

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1109-1120, April 2025.
Summary Germline variants in DDX41 (DDX41MT‐germline predisposition syndrome [GPS]) are associated with predisposition to haematological malignancies (HM), including lymphoid and myeloid neoplasms (MN). We retrospectively analysed the clinical and molecular features of 195 patients diagnosed and treated at Mayo Clinic with DDX41MT‐GPS.
Yael Kusne   +16 more
wiley   +1 more source

Outcomes of daratumumab–bortezomib–thalidomide–dexamethasone in treatment‐naive systemic AL amyloidosis

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1141-1148, April 2025.
Summary Systemic light chain (AL) amyloidosis is an incurable disorder caused by extra‐cellular deposition of light‐chain aggregates in critical organs. An immunomodulatory agent‐based quadruplet including anti‐CD38 therapy has not been investigated as a first‐line treatment in AL amyloidosis.
Jahanzaib Khwaja   +13 more
wiley   +1 more source

The IKZF1 N159S mutation is associated with poor outcome and a distinct molecular profile in adult patients with AML

open access: yesBritish Journal of Haematology, Volume 206, Issue 5, Page 1373-1379, May 2025.
Summary IKZF1 mutations are recurrent alterations in acute myeloid leukaemia (AML), and hotspot point mutation, N159S, has recently been associated with unique gene expression and adverse risk. To better understand the molecular and clinical associations of IKZF1 N159S‐mutated AML, we performed a pooled analysis of 4136 AML patients.
Sebastian Stasik   +18 more
wiley   +1 more source

Microfluidic Device for On-Chip Immunophenotyping and Cytogenetic Analysis of Rare Biological Cells. [PDF]

open access: yesCells, 2020
M Weerakoon-Ratnayake K   +11 more
europepmc   +1 more source

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