Results 311 to 320 of about 154,528 (340)
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Cytogenetic analysis of dermatofibrosarcoma protuberans
Cancer Genetics and Cytogenetics, 1990A case of dermatofibrosarcoma protuberans that occurred in an old burn scar over the anterior chest wall of a 46-year-old man is reported. Cytogenetic analysis of the tumor cells showed the presence of two abnormal clones: 47,XY, +8 and 48,XY, +8, +r.
J A, Bridge, J R, Neff, A A, Sandberg
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Overview of Cytogenetic Chromosome Analysis
Current Protocols in Cell Biology, 2004AbstractThis unit provides a brief overview of cytogenetic analysis of interphase ansd metaphase chromosomes. It includes a description of the methods provided in the units that follow.
Jane, Bayani, Jeremy A, Squire
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Cytogenetic Analysis of Tumor Clonality
2011All or almost all neoplasias subjected to systematic cytogenetic scrutiny have been found to harbor acquired chromosomal aberrations. The paradigm stemming from the study of hematopoietic malignancies and sarcomas is that cancers are of monoclonal origin (i.e., they have developed from a single transformed somatic progenitor) because all the neoplastic
Manuel R, Teixeira, Sverre, Heim
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Cytogenetic analysis of renal angiomyolipoma
Genes, Chromosomes and Cancer, 1992AbstractChromosome analysis of a benign, unilateral, renal angiomyolipoma revealed the karyotype 44,XX, –8, –12, –14, –21, + der (8q14q), + der(12)(12pter → 12q14‐15:: 12q24 → 12q14–15::21q21 → 21 qter). This indicates that structural changes of 12q13‐15, which are so frequently observed in the common malignant and benign lipogenic tumors, may also ...
M, Debiec-Rychter +2 more
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Cytogenetic Analysis and Reporting
2011Use of appropriate methods to produce analysable metaphase spreads and high-quality fluorescence in situ hybridization (FISH) and array results is critical to successful cytogenetic analysis of haematological malignancies, but the analysis and reporting of the findings of these tests are equally important as it is the final report that clinicians rely ...
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Cytogenetic Analysis of a Parachordoma
Cancer Genetics and Cytogenetics, 1998We report the cytogenetic and histopathological findings in a 7-year-old female child with an intranasal tumor that is most consistent with a parachordoma. Karyotypic analysis of the tumor revealed clonal numerical and structural chromosome abnormalities. Seven cells displayed recurrent changes: der(2)t(2;4), del(3q), and the loss of chromosomes 9, 10,
F, Tihy +5 more
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1995
Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Abstract In situ hybridization was first demonstrated in 1969 by Gall and Pardue (1). With further refinement (2), isotopic in situ hybridization became a useful tool for gene mapping. However, the relatively coarse map position generated by this method, coupled with the tedious and difficult nature of the technique, limited its ...
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Cytogenetic Analysis of Cell Lines
2004Cytogenetic analysis forms an essential part of characterizing and identifying cell lines, in particular those established from tumors. In addition, karyotypic analysis can be used to distinguish individual subclones and to monitor stability. This chapter describes basic cytogenetic procedures suited to cells in continuous culture.
Roderick A F, MacLeod, Hans G, Drexler
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Rinsho byori. The Japanese journal of clinical pathology, 2001
We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our ...
S, Miyanishi, A, Okumura
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Cytogenetic analysis by chromosome painting
Cytometry, 1994AbstractChromosome painting is a term used to describe the direct visualisation using in situ hybridisation of specific chromosomes in metaphase spreads and in interphase nuclei. Chromosome painting, coupled with fluorescence in situ hybridisation (FISH), is now used routinely to enhance the identification of chromosomal rearrangements, the assignment ...
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