Results 31 to 40 of about 154,528 (340)

Features of cytogenetic diagnosis of simultaneous chronic lymphocytic leukemia and myelodysplastic syndrome: clinical case report

Онкогематология, 2019
In chronic lymphocytic leukemia, the risk of second tumors including hematological malignancies, with which the use of purine nucleosides and alkylating agents in treatment of chronic lymphocytic leukemia is most often associated, is significantly ...
M. A. Kislitsyna, T. N. Obukhova, A. V. Kokhno, L. A. Grebenyuk, A. V. Luchkin, L. A. Kuzmina, V. N. Dvirnyk, A. M. Kovrigina, I. V. Galtseva, B. V. Biderman, V. V. Troitskaya, E. N. Parovichnikova   +11 more
doaj   +1 more source

Comparison of established and emerging biodosimetry assays [PDF]

, 2013
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric chromosome assay (DCA) and cytokinesis-block ...
Abend, M, Badie, C, Balagurunathan, Y, Barnard, S, Beinke, C, Bernard, N, Boulay-Greene, H, Braselmann, H, Brengues, M, De Amicis, A, De Sanctis, S, Greither, R, Herodin, F, Jones, A, Kabacik, S, Knie, T, Kulka, U, Lista, F, Martigne, P, Meineke, V, Missel, A, Moquet, J, Oestreicher, U, Peinnequin, A, Poyot, T, Roessler, U, Romm, H, Rothkamm, K, Scherthan, H, Terbrueggen, B, Thierens, Hubert, Valente, M, Vral, Anne, Zenhausern, F   +33 more
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Clinical findings associated with a de novo partial trisomy 10p11.22p15.3 and monosomy 7p22.3 detected by chromosomal microarray analysis. [PDF]

, 2011
We present the case of an 18-month-old boy with dysmorphic facial features, developmental delay, growth retardation, bilateral clubfeet, thrombocytopenia, and strabismus, whose array CGH analysis revealed concurrent de novo trisomy 10p11.22p15.3 and ...
Dipple, Katrina M, Kohannim, Omid, Peredo, Jane, Quintero-Rivera, Fabiola   +3 more
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Serum biochemical parameters in pregnant women with and without fetal chromosomal abnornalities

Фундаментальная и клиническая медицина, 2022
Aim. To analyse the levels of serum beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein A (PAPP-A) in pregnant women without fetal chromosomal abnormalities and with fetal trisomy 21 (Down syndrome) or 18 (Edwards syndrome ...
A. N. Volkov, O. I. Rytenkova, E. V. Tsurkan, T. A. Babarykina, G. S. Surzhikova   +4 more
doaj   +1 more source

Chromosomal variations and genetic diversity in subpopulations of Senna alexandrina Mill. from Western Thar, India

Caryologia
Homologous recombination promotes genetic diversity by exchanging genetic material between homologs, ensuring unique combinations of alleles in offspring.
Sunita Arora, Monika Vyas, Meena Barupal
doaj   +1 more source

Management of imatinib-resistant CML patients [PDF]

, 2007
Imatinib has had marked impact on outcomes in chronic myelogenous leukemia (CML) patients for all stages of the disease and is endorsed by international treatment guidelines as the first line option.
Branford S, Burger H, Burgess MR, Cortes J, Crossman LC, Donato NJ, Druker BJ, Gambacorti-Passerini C, Giles F, Hochhaus A, Hughes TP, Iacobucci I, Kantarjian H, Lahaye T, Mahon FX, Melo JV, O'Hare T, Quintas-Cardama A, Rousselot P, Sleijfer S, Soverini S, Weisberg E   +21 more
core   +1 more source

Medical Implementation of Microarray Technology

Korean Journal of Clinical Laboratory Science, 2020
Microarray technology represents a critical new advance in molecular cytogenetics. The de-velopment of this approach has provided fundamental insights into the molecular pathogenesis in clinical cytogenetics and has provided a clue to many unidentified ...
Ji Un Kang
doaj   +1 more source

A Semi-Closed Device for Chromosome Spreading for Cytogenetic Analysis

Micromachines, 2014
Metaphase chromosome spreading is the most crucial step required for successful karyotyping and FISH analysis. These two techniques are routinely used in cytogenetics to assess the chromosome abnormalities.
Dorota Kwasny, Olga Mednova, Indumathi Vedarethinam, Maria Dimaki, Asli Silahtaroglu, Zeynep Tümer, Kristoffer Almdal, Winnie E. Svendsen   +7 more
doaj   +1 more source

A new species in the major malaria vector complex sheds light on reticulated species evolution [PDF]

, 2019
Complexes of closely related species provide key insights into the rapid and independent evolution of adaptive traits. Here, we described and studied Anopheles fontenillei sp.n., a new species in the Anopheles gambiae complex that we recently discovered ...
Akone-Ella O., Ayala D., Barron M. G., Costantini C., Gonzalez J., Kengne P., Ngangue M. F., Paupy C., Pombi M., Rahola N., Simard F., Wilson-Bahun T. A.   +11 more
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Molecular Cytogenetic Study in Patients with Acute Lymphoblastic Leukemia (ALL) in Erbil Province

Zanco Journal of Pure and Applied Sciences, 2021
Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and is also important in older adults. Chromosome number or structure abnormalities are seen in approximately 90% of children and 70% of adult patients with ALL. The
Heveen Omar Hassan, Nadhum Jalal Esmael
doaj   +1 more source