Results 41 to 50 of about 22,374,088 (435)
Chromosome Segmentation Analysis Using Image Processing Techniques and Autoencoders [PDF]
arXiv, 2022 Chromosome analysis and identification from metaphase images is a critical part of cytogenetics based medical diagnosis. It is mainly used for identifying constitutional, prenatal and acquired abnormalities in the diagnosis of genetic diseases and disorders.
arxiv
Cytogenetic Analysis of Telomere Dysfunction [PDF]
, 2011 Dysfunctional telomeres arising either through natural attrition due to telomerase deficiency or by the removal of telomere binding proteins are recognized as double stranded breaks (DSBs). Repair of DSBs is crucial for the maintenance of genome stability.
Asha S. Multani, Sandy Chang
openaire +5 more sources
CaryologiaHomologous recombination promotes genetic diversity by exchanging genetic material between homologs, ensuring unique combinations of alleles in offspring.
Sunita Arora, Monika Vyas, Meena Barupal
doaj +1 more source
Blood, 2013 The identification of new genetic lesions in chronic lymphocytic leukemia (CLL) prompts a comprehensive and dynamic prognostic algorithm including gene mutations and chromosomal abnormalities and their changes during clonal evolution.
D. Rossi +23 more
semanticscholar +1 more source
Genetics of autistic disorders : review and clinical implications [PDF]
, 2009 Twin and family studies in autistic disorders (AD) have elucidated a high heritability of AD. In this literature review, we will present an overview on molecular genetic studies in AD and highlight the most recent findings of an increased rate of copy ...
Duketis, Eftichia +4 more
core +4 more sources
Blood Cancer Journal, 2017 Blinatumomab-induced lineage switch of B-ALL with t(4:11)(q21;q23) KMT2A/AFF1 into an aggressive AML: pre- and post-switch phenotypic, cytogenetic and molecular ...
C. Haddox +9 more
semanticscholar +1 more source
Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]
, 1990 Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas +5 more
core +1 more source
A Reliable Regeneration Method in Genome-Editable Bell Pepper ‘Dempsey’
Horticulturae, 2021 A reliable regeneration technique is critical for the improvement of pepper traits in the genome editing era. Recently, we reported that peppers were successfully and specifically edited using CRISPR tools, CRISPR/Cas9 and CRISPR/Cas12a (LbCpf1 ...
Kang-Hee Won +5 more
doaj +1 more source
Deep Anomaly Generation: An Image Translation Approach of Synthesizing Abnormal Banded Chromosome Images [PDF]
arXiv, 2021 Advances in deep-learning-based pipelines have led to breakthroughs in a variety of microscopy image diagnostics. However, a sufficiently big training data set is usually difficult to obtain due to high annotation costs. In the case of banded chromosome images, the creation of big enough libraries is difficult for multiple pathologies due to the rarity
arxiv
Differential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure-response analysis of a Phase III study. [PDF]
, 2013 PurposeDasatinib is a prototypic short half-life BCR-ABL1 tyrosine kinase inhibitor. The recommended dose of dasatinib for chronic myeloid leukemia in chronic phase was changed from 70 mg twice daily to 100 mg once daily following a Phase III dose ...
Chen, Tai-Tsang +5 more
core +2 more sources