Results 61 to 70 of about 22,374,088 (435)

Genetic and cytological diversity in cherry tree accessions (Eugenia involucrata DC) in Rio Grande do Sul [PDF]

Crop Breeding and Applied Biotechnology, 2016
This study aimed to evaluate the genetic and cytological diversity and stability of 35 cherry tree accessions collected in Rio Grande do Sul. We used 15 RAPD (Random Amplified Polymorphic DNA) molecular markers and performed cytological analysis and ...
Divanilde Guerra, Paulo Vitor Dutra de Souza, Sérgio Francisco Schwarz, Maria Teresa Schifino-Wittmann, Claudio André Werlang, Pedro Augusto Veit   +5 more
doaj   +1 more source

Cytogenetic techniques in current biomedical research. PART III: numerical alterations of human karyotype

Фундаментальная и клиническая медицина, 2022
Numerical abnormalities of karyotype are the result of genome mutations. Unlike gene and chromosomal abnormalities, genome mutations do not disrupt the structure of DNA or chromosomes. The cause of numerical changes in the karyotype is a violation of the
A. N. Volkov, O. I. Rytenkova
doaj   +1 more source

Comparison of established and emerging biodosimetry assays [PDF]

, 2013
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric chromosome assay (DCA) and cytokinesis-block ...
Abend, M, Badie, C, Balagurunathan, Y, Barnard, S, Beinke, C, Bernard, N, Boulay-Greene, H, Braselmann, H, Brengues, M, De Amicis, A, De Sanctis, S, Greither, R, Herodin, F, Jones, A, Kabacik, S, Knie, T, Kulka, U, Lista, F, Martigne, P, Meineke, V, Missel, A, Moquet, J, Oestreicher, U, Peinnequin, A, Poyot, T, Roessler, U, Romm, H, Rothkamm, K, Scherthan, H, Terbrueggen, B, Thierens, Hubert, Valente, M, Vral, Anne, Zenhausern, F   +33 more
core   +2 more sources

Cytogenetic analysis of 531 Chinese women with premature ovarian failure.

Human Reproduction, 2012
BACKGROUND This retrospective cohort study was to determine the frequency and types of chromosomal abnormalities in Han Chinese women with well-documented premature ovarian failure (POF).
X. Jiao, C. Qin, Jie-ming Li, Y. Qin, Xuan Gao, Bo Zhang, X. Zhen, Yun Feng, J. Simpson, Zi-jiang Chen   +9 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A case of supernumerary derivative chromosome 22 syndrome in a child

Фундаментальная и клиническая медицина, 2023
Here we describe a rare case of an abnormal karyotype with a supernumerary derivative chromosome der(22)t(11;22), associated with Emanuel syndrome, in a boy aged 1 year.
R. V. Olennikova, O. I. Rytenkova, A. N. Volkov   +2 more
doaj   +1 more source

A Critical Review of the Impact of Candidate Copy Number Variants on Autism Spectrum Disorders [PDF]

arXiv, 2023
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder (NDD) that is caused by genetic, epigenetic, and environmental factors. Recent advances in genomic analysis have uncovered numerous candidate genes with common and/or rare mutations that increase susceptibility to ASD.
arxiv  

Management of imatinib-resistant CML patients [PDF]

, 2007
Imatinib has had marked impact on outcomes in chronic myelogenous leukemia (CML) patients for all stages of the disease and is endorsed by international treatment guidelines as the first line option.
Branford S, Burger H, Burgess MR, Cortes J, Crossman LC, Donato NJ, Druker BJ, Gambacorti-Passerini C, Giles F, Hochhaus A, Hughes TP, Iacobucci I, Kantarjian H, Lahaye T, Mahon FX, Melo JV, O'Hare T, Quintas-Cardama A, Rousselot P, Sleijfer S, Soverini S, Weisberg E   +21 more
core   +1 more source

The FBXW7‐RPAP2 Axis Controls the Growth of Hepatocellular Carcinoma Cells and Determines the Fate of Liver Cell Differentiation

Advanced Science, Volume 12, Issue 13, April 3, 2025.
The study shows that RPAP2, acting as an oncoprotein, promotes hepatocellular carcinoma (HCC) progression, with its stability being negatively regulated by FBXW7, yet positively by HSP90 and USP7. The FBXW7‐RPAP2 axis plays a crucial role in controlling HCC cell growth and influencing liver cell differentiation.
Danrui Cui, Shengpeng Shao, Ruirui Qu, Xiaoyu Chen, Shanghong Jiang, Linchen Wang, Longyuan Gong, Tianqi Li, Danyi Zhai, Wenfeng Song, Penghong Song, Yi Sun, Tingbo Liang, Xiufang Xiong, Yongchao Zhao   +14 more
wiley   +1 more source

Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation.

Human Reproduction, 2011
BACKGROUND Recent studies have suggested that biopsy of several trophectoderm (TE) cells from blastocysts followed by comparative genomic hybridization (CGH) analysis might represent an optimal strategy for aneuploidy detection, but few data on accuracy ...
E. Fragouli, S. Alfarawati, D. Daphnis, N. Goodall, A. Mania, T. Griffiths, A. Gordon, D. Wells   +7 more
semanticscholar   +1 more source