Results 1 to 10 of about 231,105 (412)

“Classical cytogenetics” is not equal to “banding cytogenetics” [PDF]

open access: yesMolecular Cytogenetics, 2017
Human cytogenetics is a field suffering from the argumentation that it 'is nowadays really outdated and to be replaced by molecular high throughput approaches'. Thus, it is to be expected that non-cytogeneticists do mistakes in nomenclature of cytogenetics, which is exposed to repeated reforms, like e.g.
T. Liehr
openaire   +4 more sources

Human molecular cytogenetics: from cells to nucleotides

open access: yesGenetics and Molecular Biology, 2014
The field of cytogenetics has focused on studying the number, structure, function and origin of chromosomal abnormalities and the evolution of chromosomes. The development of fluorescent molecules that either directly or via an intermediate molecule bind
Mariluce Riegel
doaj   +2 more sources

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features

open access: yesHaematologica, 2013
In childhood B-cell precursor acute lymphoblastic leukemia, cytogenetics is important in diagnosis and as an indicator of response to therapy, thus playing a key role in risk stratification of patients for treatment.
Claire J. Schwab   +8 more
doaj   +2 more sources

Cytogenetics of Legumes in the Phaseoloid Clade

open access: yesThe Plant Genome, 2013
Cytogenetics played an essential role in studies of chromosome structure, behavior, and evolution in numerous plant species. The advent of molecular cytogenetics combined with recent development of genomic resources has ushered in a new era of chromosome
Aiko Iwata   +2 more
doaj   +2 more sources

Outcomes in Patients with Poor-Risk Cytogenetics with or without TP53 Mutations Treated with Venetoclax and Azacitidine

open access: yesClinical Cancer Research, 2022
Purpose: To evaluate efficacy and safety of venetoclax + azacitidine in treatment-naïve patients with acute myeloid leukemia harboring poor-risk cytogenetics and TP53mut or TP53wt.
D. Pollyea   +12 more
semanticscholar   +1 more source

Cytogenetics of Pediatric Acute Myeloid Leukemia: A Review of the Current Knowledge

open access: yesGenes, 2021
Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to morphology, immunophenotyping, germline and somatic cytogenetic and genetic abnormalities.
Julie Quessada   +5 more
semanticscholar   +1 more source

Classical, Molecular, and Genomic Cytogenetics of the Pig, a Clinical Perspective

open access: yesAnimals, 2021
The chromosomes of the domestic pig (Sus scrofa domesticus) are known to be prone to reciprocal chromosome translocations and other balanced chromosome rearrangements with concomitant fertility impairment of carriers.
Brendan Donaldson   +2 more
doaj   +1 more source

Impact of high-risk cytogenetics on outcomes for children and young adults receiving CD19-directed CAR T cell therapy.

open access: yesBlood, 2021
Chimeric antigen receptor (CAR) T-cell therapy can induce durable remissions of relapsed/refractory B-acute lymphoblastic leukemia (ALL). However, case reports suggested differential outcomes mediated by leukemia cytogenetics.
Allison Barz Leahy   +15 more
semanticscholar   +1 more source

A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Although cytogenetics-based prognostication systems are well described in acute myeloid leukemia (AML), overall survival (OS) remains highly variable within risk groups.
Caroline E Sloan   +10 more
doaj   +1 more source

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