Results 31 to 40 of about 65,280 (255)
Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance
Advanced Science, EarlyView.COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu +12 more
wiley +1 more source
, 2017 Conventionally, acute myeloid leukemia (AML) patients are categorized into good-, intermediate- and poor-risk groups according to cytogenetic changes.
Hou, H-A;Lin, C-C;Chou, W-C;Liu, C-Y;Chen, C-Y;Tang, J-L;Lai, Y-J;Tseng, M-H;Huang, C-F;Chiang, Y-C;Lee, F-Y;Kuo, Y-Y;Lee, M-C;Liu, M-C;Liu, C-W;Lin, L-I;Yao, M.;Huang, S-Y;Ko, B-S;Hsu, S-C;Wu, S-J;Tsay, W.;Chen, Y-C;Tien, H-F +1 more
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a potentially curative strategy for acute myeloid leukemia (AML), but the impact of HLA disparity in the era of posttransplant cyclophosphamide (PTCy) and reduced‐toxicity conditioning remains unclear. We performed an EBMT registry study including 275 adult AML patients in first
Daniele Avenoso +21 more
wiley +1 more source
Cytogenetic findings at Down syndrome and their correlation with clinical findings
Biomolecules & Biomedicine, 2005 Down syndrome is a genetic state characterized by trisomy of chromosome 21. In the retrospective study for 12 years period (1991-2002) we have conducted correlation between cytogenetics analyses and clinical findings in our centre at 96 male and 83 ...
Amra Ćatović, Sulejman Kendić
doaj +1 more source
, 2004 Deep insight on Some lessons from uniparental disomy (UDP) in the framework of comtemporary cytogenetics and molecular ...
Engel, E
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Mutations in FLT3 are present in approximately 30% of patients with AML. The addition of midostaurin (MIDO) to intensive chemotherapy (IC) became standard of care following the RATIFY trial, but comprehensive real‐world data spanning the full adult age spectrum and including both FLT3‐ITD and FLT3‐TKD mutations remain limited.
Mónica Alejandra Romero Riquelme +49 more
wiley +1 more source
Comparative cytogenetics in avian species
, 2016 Comparative cytogenetics in avian species. 22.
Fillon, Valerie
core +3 more sources
American Journal of Hematology, EarlyView.ABSTRACT Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...
Florence Nguyen‐Khac +16 more
wiley +1 more source
An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula +8 more
wiley +1 more source
Candidate genes for infertility: an in-silico study based on cytogenetic analysis
BMC Medical Genomics, 2022 Background The cause of infertility remains unclear in a significant proportion of reproductive-age couples who fail to conceive naturally. Chromosomal aberrations have been identified as one of the main genetic causes of male and female infertility ...
Jatinder Singh Sahota +3 more
doaj +1 more source