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A Bone Marrow Study; Report of Chromosomal Variations in Hematologic Malignancies Including Acute Myeloid Leukemia, Acute Lymphoid Leukemia, and Myelodisplastic Syndrome (Northeast Iran) [PDF]
Middle East Journal of Cancer, 2021 Background: Chromosomal aberrations which occur in different hematologic malignancies are believed to be highly applicable for identifying the prognosis and treatment protocols.
Sepideh Shakeri +3 more
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A Reliable Regeneration Method in Genome-Editable Bell Pepper ‘Dempsey’
Horticulturae, 2021 A reliable regeneration technique is critical for the improvement of pepper traits in the genome editing era. Recently, we reported that peppers were successfully and specifically edited using CRISPR tools, CRISPR/Cas9 and CRISPR/Cas12a (LbCpf1 ...
Kang-Hee Won +5 more
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Фундаментальная и клиническая медицина, 2022 Numerical abnormalities of karyotype are the result of genome mutations. Unlike gene and chromosomal abnormalities, genome mutations do not disrupt the structure of DNA or chromosomes. The cause of numerical changes in the karyotype is a violation of the
A. N. Volkov, O. I. Rytenkova
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A case of supernumerary derivative chromosome 22 syndrome in a child
Фундаментальная и клиническая медицина, 2023 Here we describe a rare case of an abnormal karyotype with a supernumerary derivative chromosome der(22)t(11;22), associated with Emanuel syndrome, in a boy aged 1 year.
R. V. Olennikova +2 more
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Molecular Cytogenetic Study in Patients with Acute Lymphoblastic Leukemia (ALL) in Erbil Province
Zanco Journal of Pure and Applied Sciences, 2021 Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and is also important in older adults. Chromosome number or structure abnormalities are seen in approximately 90% of children and 70% of adult patients with ALL. The
Heveen Omar Hassan, Nadhum Jalal Esmael
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Toxicological Investigations of Aristolochia longa Root Extracts
Journal of Toxicology, 2020 Aristolochia longa L. (Aristolochiaceae) is an herbaceous plant recognized in alternative medicine for its many therapeutic virtues. The aim of this study was to determine the pharmacotoxicological effects of this plant in order to ensure safe clinical ...
Nasreddine El Omari +9 more
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Toxics, 2023 The long-term storage of unutilized pesticides raised new problems of long-term environmental contamination. The study presents the results of surveying 151 individuals in 7 villages living close to pesticide-contaminated localities. All individuals have
Aleksandr Garshin +11 more
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Cytogenetic analysis of meningiomas [PDF]
Journal of Korean Medical Science, 1992 Cytogenetic analysis of 4 cases of meningiomas from 3 male and 1 female patients is reported. One of male patients suffered from neurofibromatosis type 2. Histologically, the meningiomas were meningotheliomatous (1), transitional (2), and psammomatous (1). Chromosomal abnormalities were found in all cases with a karyotype 45,XY,-22, 45,XY,-16, 45,XX,-2,
J H, Cho +5 more
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Cytogenetic Analysis of Telomere Dysfunction [PDF]
, 2017 Dysfunctional telomeres arising either through natural attrition due to telomerase deficiency or by the removal of telomere-binding proteins are recognized as double-stranded breaks (DSBs). Repair of DSBs is crucial for the maintenance of genome stability.
Rekha, Rai +2 more
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Clinical genetic description and analysis of the case of chromosomal mosaicism mos47,XY,+8/46,XY
Бюллетень сибирской медицины, 2021 The article describes a clinical case of chromosomal mosaicism in a boy, 4 months and 3 weeks old. Cytogenetic analysis of peripheral blood lymphocytes of the child made it possible to establish the karyotype mos47,XY,+8/46,XY with an approximately equal
s L. Nersesyan +2 more
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