Results 91 to 100 of about 128,557 (342)

Karyotype evolution in progress: A new diploid number in Belostoma candidulum (Heteroptera: Belostomatidae) from Argentina leading to new insights into its ecology and evolution [PDF]

open access: yes, 2014
A novel chromosome complement (2n = 14 = 12 + XY/XX; male/female sex chromosomes), male meiosis behaviour, heterochromatin characterization, and frequency and distribution of chiasmata are described for the first time in specimens from a natural ...
Bressa, Maria Jose   +1 more
core   +1 more source

Unraveling genotype–phenotype associations and predictive modeling of outcome in acute myeloid leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) comprises 32% of adult leukemia cases, with a 5‐year survival rate of only 20–30%. Here, the immunophenotypic landscape of this heterogeneous malignancy is explored in a single‐center cohort using a novel quantitative computational pipeline.
Artuur Couckuyt   +10 more
wiley   +1 more source

ins(9;4)(q33;q12q25) [PDF]

open access: yes, 2010
Review on ins(9;4)(q33;q12q25), with data on clinics, and the genes ...
Huret, JL
core   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Optimization of the indications for allogeneic stem cell transplantation in Acute Myeloid Leukemia based on interactive diagnostic strategies [PDF]

open access: yes, 2011
The indications for allogeneic stem cell transplantation (SCT) in Acute Myeloid Leukemia (AML) represent a real challenge due to the clinical and genetic heterogeneity of the disorder.
Bacher, Ulrike   +5 more
core  

Biomarkers of leukemia risk: benzene as a model. [PDF]

open access: yes, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core   +3 more sources

CYTOGENETICS OF SPECIATION

open access: yesAustralian Journal of Entomology, 1970
iThe essence of speciation lies in the origin of genetic isolating mechanisms. Argument has raged as to whether the primary isolating mechanisms which initiate specific divergence operate at the pre‐mating or post‐mating level and whether complete geographic isolation necessarily precedes divergence.
openaire   +3 more sources

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li   +7 more
wiley   +1 more source

BCR-ABL1 gene rearrangement as a subclonal change in ETV6-RUNX1–positive B-cell acute lymphoblastic leukemia

open access: yesBlood Advances, 2016
: We report here on a case of ETV6-RUNX1–positive B-cell acute lymphoblastic leukemia (B-ALL) that has acquired a BCR-ABL1 gene rearrangement as a subclonal change.
Karen A. Dun   +5 more
doaj  

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