Results 91 to 100 of about 132,265 (338)

Cytogenetics of Legumes in the Phaseoloid Clade

The Plant Genome, 2013
Cytogenetics played an essential role in studies of chromosome structure, behavior, and evolution in numerous plant species. The advent of molecular cytogenetics combined with recent development of genomic resources has ushered in a new era of chromosome
Aiko Iwata, Christopher M. Greenland, Scott A. Jackson   +2 more
doaj   +1 more source

Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia [PDF]

, 2001
Chronic myeloid leukemia (CML) is characterized by formation of the BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22.
Bench, AJ, Campbell, LJ, Grace, C, Green, AR, Huntly, BJP, Nacheva, EP, Prince, HM, Reid, AG, Shepherd, P, Szer, J, Telford, N, Turner, P   +11 more
core   +1 more source

The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia

International Journal of Cancer, EarlyView.
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch, Ana Carolina Rodrigues, Priscila Elias Ferreira Stricker, Alexandre Luiz Korte Azevedo, Daniel Pacheco Bruschi, Jaqueline Carvalho de Oliveira   +5 more
wiley   +1 more source

An Additional Report of a Female With a Complex XY Translocation Is Presented Who Has Successfully Completed a Pregnancy With Significant Y Chromosome Material Gain and Partial X Deletion

American Journal of Medical Genetics Part A, EarlyView.
John Coleman, Nicola Walsh, Deborah M. Lambert, Andrew Green, Sally Ann Lynch   +4 more
wiley   +1 more source

Clinical and Genetic Significance of Chromosomal Microarray Screening of Asymptomatic Newborns

Journal of Clinical Laboratory Analysis, EarlyView.
Among 99 asymptomatic newborns with abnormal low‐resolution chromosomal microarray (LR‐CMA) screening, 70.7% harbored microduplication/microdeletions with syndromic implications. However, only a minority exhibited developmental concerns during early follow‐up, highlighting the need for cautious interpretation.
Naye Choi, Hwa Young Kim, Jung Min Ko
wiley   +1 more source

Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia [PDF]

, 2017
Telomeres are protective repeats of TTAGGG sequences located at the end of human chromosomes. They are essential to maintain chromosomal integrity and genome stability.
Bezares, Raimundo F., Dos Santos, Patricia Carolina, Palau Nagore, Maria Virginia, Panero, Julieta, Slavutsky, Irma Rosa, Stanganelli, Carmen Graciela, Stella, Flavia   +6 more
core   +1 more source

Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia. [PDF]

, 2009
We observed that high-dose methylprednisolone (HDMP) and rituximab was well tolerated and had promising activity when used in combination to treat patients with fludarabine-refractory chronic lymphocytic leukemia (CLL).
Bole, J, Castro, JE, Jain, S, James, DF, Kipps, TJ, Rassenti, L, Sandoval-Sus, JD   +6 more
core  

Leukemia in Older Adults: Global, National, and Regional Disease Burden Patterns During 1990–2019 and Forecasted Trends to 2030

Medicine Advances, EarlyView.
After analyzing the burden of leukemia in the elderly aged 60–89 years from 1990 to 2019 using the Global Burden of Disease database, we found that although the burden of chronic myeloid leukemia has decreased over the past 30 years, the burden of other types of leukemia has continued to increase to varying degrees.
Jing Wei, Qijian Feng, Ziyuan Lu
wiley   +1 more source

Correction to: Novel deletion of exon 3 in TYR gene causing Oculocutaneous albinism 1B in an Indian family along with intellectual disability associated with chromosomal copy number variations

BMC Medical Genomics, 2022
Somprakash Dhangar, Purvi Panchal, Jagdeeshwar Ghatanatti, Jitendra Suralkar, Anjali Shah, Babu Rao Vundinti   +5 more
doaj   +1 more source

Two new records for the flora of Paraguay: Stemodia diplohyptoides and S. lobelioides (Plantaginaceae:Gratioleae)

Nordic Journal of Botany, EarlyView.
Stemodia diplohyptoides M.M.Sosa & Dematt. and S. lobelioides Lehm. (Gratioleae, Plantaginaceae) are reported for the first time in Paraguay, found in Alto Paraná and Presidente Hayes departments, respectively. These new records extend the known geographical range of both species, representing the northern records to date, S.
Y. Carlés Bechara, S. Y. Gauto, V. R. Kubota, O. A. Feltes González, M. M. Sosa   +4 more
wiley   +1 more source