Results 101 to 110 of about 44,893 (265)

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

British Journal of Haematology, EarlyView.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda, Eduardo Arellano‐Rodrigo, Manuel Pérez‐Encinas, José‐María Raya, María‐Teresa Gómez‐Casares, Francisca Ferrer‐Marín, Alberto Hernández‐Sánchez, María‐Laura Fox, Anna Angona, Beatriz Cuevas, María‐Isabel Mata‐Vázquez, Rosa Ayala, Natalia de las Heras, Elvira Mora, Valentín García‐Gutiérrez, Alicia Senín, Jasson Villarreal, Blanca Xicoy, Raúl Pérez‐López, María García‐Fortes, Sonia González de Villambrosia, Elena Magro, María‐José Ramírez, Paula Gómez, Angel Ramírez‐Payer, Clara Martínez‐Valverde, Lucía Pérez‐Lamas, Carmen García‐Hernández, Mercedes Gasior, Luis‐Miguel Juárez‐Salcedo, Francisco Ibáñez, María‐Luisa Antelo, Lucía Guerrero, Alberto Alvarez‐Larrán, Arturo Pereira, on behalf of the Spanish MPN Group (GEMFIN)   +35 more
wiley   +1 more source

Molecular heterogeneity and prognostic biomarkers in primary meningeal melanocytic tumors

Brain Pathology, EarlyView.
Integrated molecular profiling reveals biological heterogeneity among primary meningeal melanocytic tumors, identifying intermediate‐grade PMMT subgroups with distinct recurrence risk. Molecular alterations including SF3B1 mutations and chromosome 8q gains support prognostic stratification, while PRKAR1A alterations and chromosome 17/21q losses aid ...
Rosina Paterra, Monica Patanè, Anna Stroppa, Gianluca Marucci, Serena Ammendola, Sofia Asioli, Valeria Barresi   +6 more
wiley   +1 more source

O55: Evaluation of a large cohort of spontaneous pregnancy losses: Intriguing findings from both chromosome and microarray studies

Genetics in Medicine Open
Stuart Schwartz, Alexandra Arreola, Inder Gadi, Gloria Haskell, Bing Huang, Judith Knops, Zach Ou, Andrea Penton, Karen Phillips, Amanda Sussman, James Tepperberg   +10 more
doaj   +1 more source

Long‐Term Local Control and Mortality After Transpupillary Thermotherapy of Small Uveal Melanomas

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Transpupillary thermotherapy (TTT) is used for selected small choroidal melanocytic tumours, either as primary treatment or as an adjunct to plaque brachytherapy. We compared long‐term local recurrence and mortality outcomes after primary TTT alone, plaque brachytherapy combined with TTT (brachy+TTT), and plaque brachytherapy alone (
Maria Fili, Malin Ermedahl Conradi, Maya Klaff Dahl, Shiva Sabazade, Manuel Casselholm De Salles, Gustav Stålhammar   +5 more
wiley   +1 more source

Early venetoclax dose escalation at minimal residual disease progression may benefit selected acute myeloid leukaemia patients

British Journal of Haematology, EarlyView.
Sari Kytölä, Anu Partanen, Milla E. L. Kuusisto, Sirpa Koskela, Annasofia Holopainen, Ida Vänttinen, Tanja Ruokoranta, Pia Ettala, Johanna Rimpiläinen, Timo Siitonen, Marja Pyörälä, Heikki Kuusanmäki, Mika Kontro   +12 more
wiley   +1 more source

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques ‐ Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee, Joevy Z. Lim, Peter W. Hadden, Jie Zhang   +3 more
wiley   +1 more source

P592: Cytogenetic and microarray analysis of prenatally detected congenital heart defects (CHD): Diagnostic findings and variation among CHD subtypes

Genetics in Medicine Open
Stuart Schwartz, Alexandra Arreola, Inder Gadi, Gloria Haskell, Bing Huang, Judith Knops, Andrea Penton, Karen Phillips   +7 more
doaj   +1 more source

Cancer Cytogenetics: Deep Roots, New Branches in the Age of Omics. [PDF]

Cancer Genomics Proteomics
Panagopoulos I.
europepmc   +1 more source

Pure erythroid leukaemia in early infancy: Diagnostic pitfalls and clinical challenges

British Journal of Haematology, EarlyView.
Riccardo De Carli, Baptiste Le Calvez, Elodie Lainey, Catherine Settegrana, Marion Strullu, Marlene Pouthier   +5 more
wiley   +1 more source

Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1‐Related Noonan Syndrome

Clinical Genetics, EarlyView.
This study illustrates the phenotypic variability of LZTR1‐related Noonan syndrome type 10 in two pediatric patients, including presentations without congenital heart defects. The findings emphasize the importance of whole‐exome sequencing and longitudinal re‐evaluation of variants of uncertain significance in achieving accurate diagnosis.
Karolina Skrzyńska, Barbara Kalina‐Faska, Ewa Błaszczyk, Aneta Gawlik‐Starzyk   +3 more
wiley   +1 more source