Results 141 to 150 of about 73,620 (322)
A CYTOGENETIC STUDY OF A CHROMOSOME FRAGMENT IN MAIZE [PDF]
, 1936 M. M. Rhoades
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Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, EarlyView.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Enhancing human gut health: Global innovations in dysbiosis management
iMeta, EarlyView.The microbiota, comprising all the microorganisms within the body, plays a critical role in maintaining good health. Dysbiosis represents a condition resulting from an imbalance or alteration of the microbiota. This study comprehensively investigates the patent literature on dysbiosis over the past 20 years.
Reda El Boukhari +66 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.The pregnant women with advanced maternal age who underwent amniocentesis at the Prenatal Diagnosis Center of Huizhou Central People's Hospital were enrolled in this study. The women were grouped based on different age ranges and prenatal diagnosis factor.
Caihong Liu +5 more
wiley +1 more source
The constitutional gain‐of‐function variant p.Glu1099Lys in NSD2 is associated with a novel syndrome
Clinical Genetics, Volume 103, Issue 2, Page 226-230, February 2023., 2023 The gain‐of‐function variant p.Glu1099Lys in NSD2 was described in hematologic malignancies while germline loss‐of‐function was associated with Wolf–Hirschhorn syndrome and Rauch–Steindl syndrome. Now we associate this variant identified in the germinal of two individuals with a novel syndrome characterized by intellectual disability, coarse/ square ...
Bernt Popp +16 more
wiley +1 more source
Cytogenetic, Hematobiochemical, and Histopathological Assessment of Albino Rats (Rattus norvegicus) Fed on Gluten Extracts [PDF]
arXivBackground: Literature shows that most of the information on the toxicity of gluten is generated from survey and observational studies, resulting in inconsistent outcomes and a decrease in the acceptability of gluten-rich foods. To determine gluten's safety, an in-depth in vitro and in vivo toxicological examination is required. This enables scientists
arxiv